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Table 2 Characteristics of the sample according to the use of statins

From: Statins are associated with reduced likelihood of sarcopenia in a sample of heart failure outpatients: a cross-sectional study

 

Not medicated with statins

(n = 47)

Statin users

(n = 89)

p-value

Sex, n (%)

  

0.237

 Women

19 (40.4)

27 (30.3)

 

 Men

28 (56.9)

62 (67.7)

 

Age, years, Md (IQR)

51.0 (39.0, 64.0)

62.0 (54.0, 69.0)

 < 0.001

Age categories, n (%)

  

0.025

  < 65 years

37 (78.7)

53 (59.6)

 

  ≥ 65 years

10 (21.3)

36 (40.4)

 

HF aetiology, n (%)

  

 < 0.001

 Dilated cardiomyopathy

29 (61.7)

43 (48.3)

 

 Ischaemic*

4 (8.5)

34 (38.2)

 

 Myocarditis*

4 (8.5)

1 (1.1)

 

 Hypertrophic cardiomyopathy

4 (8.5)

5 (5.6)

 

 Others

6 (12.8)

6 (6.7)

 

LVEF categories, n (%)

  

0.404

 HFrEF + HFmrEF

36 (78.3)

63 (71.6)

 

 HFpEF

10 (21.7)

25 (28.4)

 

NYHA classification, n (%)

  

0.455

 Class I

16 (34.8)

31 (35.2)

 

 Class II

20 (43.5)

45 (51.1)

 

 Class III

10 (21.7)

12 (13.6)

 

Incident myocardial infarction, n (%)

2 (4.5)

30 (33.7)

 < 0.001

Polypharmacy, n (%)

25 (54.3)

76 (85.4)

 < 0.001

Type 2 Diabetes Mellitus

9 (19.6)

30 (33.7)

0.086

Number of medicines/day, Md (IQR)

5.0 (3.8, 8.0)

7.0 (5.5, 9.5)

 < 0.001

Physical activity, n (%)

  

0.175

 Inactive

30 (63.8)

46 (51.7)

 

 Minimally active + active

17 (36.2)

43 (48.3)

 

Body Mass Index, Kg.m−2, M (SD)

28.9 (4.7)

29.4 (4.2)

0.526

Fat intake, g/day, Md (IQR)

59.7 (47.5, 86.4)

54.1 (37.0, 74.4)

0.149

  1. Values are presented as: n (%) = number (percentage); M (SD) = Mean (Standard Deviation); Md (IQR) = Median (Lower quartile, Upper quartile). HF = Heart Failure; LVEF = Left Ventricular Ejection Fraction; HFrEF = Heart Failure with reduced Ejection Fraction; HFmrEF = Heart Failure with mildly reduced Ejection Fraction; HFpEF = Heart Failure with preserved Ejection Fraction. Missing values: LVEF n = 3; NYHA n = 2; Incident myocardial infarction n = 2
  2. *Results differ significantly between subsets of dependent variable, as per Bonferroni adjusted p-values