Antihypertensive medicine use differs between Ghana and Nigeria

Table 2 Use of antihypertensive medicines by medicines (defined daily dose [DDD] and proportion within class [%]) for single products in Ghana and Nigeria plus top ten ranking and proportion

Class	Medicine	Ghana				Nigeria
Class	Medicine	Use (DDD)	% within class	Rank	% of top 10	Use (DDD)	% within class	Rank	% of top 10
ARB	Candesartan	260,561	68.6%	1	27.7	33,203	3.5%
	Losartan	92,384	24.3%	5	9.8	517,910	55.1%	1	17.8
	Valsartan	27,084	7.1%	9	2.9	239,830	25.5%	6	8.3
	Telmisartan	–	0			147,807	15.7%	8	5.1
	Irbesartan	–	0			1796	0.2%
	Total	380,029				940,546
CCB	Nifedipine	160,490	51.7%	2	17.1	408,500	50.8%	3	14.1
	Amlodipine	101,778	32.8%	4	10.8	394,731	49.1%	5	13.6
	Felodipine	48,377	15.6%	7	5.1	600	0.1%
	Nimodipine	–	0			15	0.0%
	Total	310,645				803,845
ACEi	Lisinopril	129,004	99.4%	3	13.7	418,073	81.3%	2	14.4
	Ramipril	779	0.6%			88,831	17.3%
	Perindopril	–	0.0%			7170	1.4%
	Captopril	–	0.0%			178	0.0%
	Enalapril	–	0.0%			170	0.0%
	Total	129,783				514,422
DU	Indapamide	65,332	90.4%	6	6.9	74,382	11.4%
	Furosemide	1968	2.7%			398,932	61.2%	4	13.7
	Hydrochlorothiazide	–	0.0%			148,244	22.8%	7^a	5.1
	Bendroflumethiazide	4972	6.9%			21,731	3.3%
	Metolazone	–	0.0%			5202	0.8%
	Torasemide	–	0.0%			2917	0.4%
	Total	72,272				651,408
BB	Atenolol	26,810	41.0%	10	2.8	121,556	57.5%	9	4.2
	Carvedilol	29,275	44.8%	8	3.0	22,484	10.6%	6	8.7
	Metoprolol	7911	12.1%			40,816	19.3%
	Propanolol	21	0.0%			11,274	5.3%
	Bisoprolol	1377	2.1%			7016	3.3%
	Labetalol	–	0.0%			8177	3.9%
Total		65,393				211,322
AAC	Methyldopa	4528	100			107,321	100	10	3.7

ARB Angiotensin receptor blockers, CCB calcium channel blocker, ACEI angiotensin-converting enzyme inhibitor, BB beta-blocker, DU Diuretic, AAP, AAC and ST are not conventional abbreviations. AAC will involve centrally acting drugs like methyldopa
^aAmiloride + HCT was ranked #7 but removed as it is a combination product

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