Table 1 Baseline characteristics of the included trials
Study | Publication year | Type | Country | Lesion type | DES type | Study total size | Randomization | MACE | Follow up (month) |
|---|---|---|---|---|---|---|---|---|---|
AIR-CTO [13] | 2015 | RCT | China | CTO | First/Second generation | 115/115 | IVUS VS Angiography | All-cause death, MI, TLR, ST | 24 |
AVIO [14] | 2013 | RCT | European countries | Complex lesionsa | First generation | 142/142 | IVUS VS Angiography | Cardiac death, MI or TVR | 24 |
CTO-IVUS [15] | 2015 | RCT | Korea, America | CTO | New-generation | 201/201 | IVUS VS Angiography | Cardiac death, MI or TVR | 12 |
HOME DES IVUS [23] | 2010 | RCT | Czech Republic | Complex lesionsa | First generation | 105/105 | IVUS VS Angiography | All-cause death, MI or TLR | 18 |
ILUMIEN III [21] | 2021 | RCT | America | Non-complex lesions | NR | 289/142 | IVUS + OCT VS Angiography | Cardiac death, MI or TLR | 12 |
iSIGHT [34] | 2021 | RCT | Brazil | Long lesions, Non–unprotected left main | Second/ New-generation | 101/49 | IVUS + OCT VS Angiography | Cardiac death, MI and TLR | 30 |
IVUS-XPL [16] | 2015 | RCT | Korea | Long lesions | New-generation | 700/700 | IVUS VS Angiography | Cardiac death, MI or TLR | 12 |
Kala et al. [22] | 2016 | RCT | Czech Republic, America | All comer | Second/ New-generation | 105/96 | OCT VS Angiography | All-cause death, MI, and TLR | 9 |
Kim et al. [17] | 2013 | RCT | Korea | Long lesions | Second generation | 297/246 | IVUS VS Angiography | Cardiac death, MI, TVR or ST | 12 |
Liu et al. [18] | 2019 | RCT | China | Unprotected left main | NR | 167/169 | IVUS VS Angiography | Cardiac death, MI or TVR | 12 |
RESET [24] | 2013 | RCT | Korea | Non-complex lesions | Second generation | 662/912 | IVUS VS Angiography | Cardiac death, MI or TVR | 12 |
Tan et al. [19] | 2015 | RCT | China | Unprotected left main | First generation | 61/62 | IVUS VS Angiography | All-cause death, MI, TLR | 24 |
ULTIMATE [20] | 2021 | RCT | China | Long lesions | Second generation | 714/709 | IVUS VS Angiography | Cardiac death, MI or TVR | 36 |