Table 2 GO analysis of significant DEGs in CA (Cellular component)

Plasma membrane

1.27E-04

GYPC, PROS1, LYPD1, DYSF, ADD3, RASGRP3, IL1RL1, UCHL1, BASP1, PODXL, LAMP3, MRC1, EPB41L3, SLIT2, THSD7A, SLC16A3, NDC1, LYN, ANGPT2, JUP, IL1R1, ANXA3, SLC6A15, PDE2A, TRPV2, HLA-B, EMP3, SULF1, LYVE1, DKK1, GNG11, TGFBR2, VAMP8, PROCR, TSPAN13, MELK, ADGRF5, ANOS1, SPRY1, PLPP3

Proteinaceous extracellular matrix

6.48E-04

IL1RL1, TFPI2, ANOS1, TIMP3, COL4A5, SLIT2, LTBP1, MMP10

Extracellular space

0.002381461

TGFB2, ANGPT2, GPX3, PROS1, IGFBP2, HMGB2, SULF1, FGF2, DKK1, MMP10, GREM1, PODXL, DPYSL3, NAMPT, ANOS1, TIMP3, SLIT2

Extracellular region

0.002432724

TGFB2, ANGPT2, IL1R1, GPX3, FST, PROS1, IGFBP2, LYPD1, NID1, FGF2, LTBP1, DKK1, MMP10, PROCR, ANOS1, TIMP3, COL4A5, SLIT2, APOL3

Cell surface

0.002751077

GREM1, PROCR, BACE2, IL1R1, ADGRF5, MRC1, TRPV2, HLA-B, SLIT2, SULF1

Extracellular matrix

0.005539698

TGFB2, JUP, TFPI2, TIMP3, NID1, LTBP1, MMP10

Cytoplasm

0.007831471

PCNA, HMGB2, HJURP, ADIRF, ADD3, FGF2, MYLK, UCHL1, PTTG1, HEY1, BASP1, PODXL, DPYSL3, NAMPT, EPB41L3, SACS, ANKRD1, SH3BP5, OIP5, SLIT2, APOL3, NDC1, LYN, RRM2, JUP, ANXA3, PDE2A, AKR1C2, SHCBP1, GULP1, VAMP8, CCNA2, FABP4, FABP5, UBE2S, RBP1, CDK1, SPRY1, NUPR1, ITGB3BP, PFN2

Membrane

0.026710555

NDC1, GYPC, IL1R1, ANXA3, NCAPG2, HLA-B, EMP3, ADD3, LYVE1, VAMP8, TSPAN13, MELK, LAMP3, CDK1, SLIT2, PLPP3, SLC16A3, APOL3, CEP55, ITGB3BP

Nucleoplasm

0.041897672

RFC3, RRM2, PCNA, NCAPG2, HMGB2, HJURP, ADIRF, ADD3, CKS1B, RAD51AP1, CCNA2, UCHL1, HEY1, FABP5, NAMPT, RBP1, DEPDC1, ANKRD1, CDK1, OIP5, SPRY1, SRSF6, ITGB3BP

Integral component of plasma membrane

0.042489931

GYPC, IL1R1, SLC6A15, TRPV2, HLA-B, LYVE1, TGFBR2, RASGRP3, PROCR, TSPAN13, PODXL, MRC1, PLPP3, SLC16A3