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Table 4 The association between the use of cardiac drug therapies and symptoms of anxiety

From: The association between cardiac drug therapy and anxiety among cardiac patients: results from the national DenHeart survey

 

Model 1a

Model 2b

Model 3c

OR (95% CI)

OR (95% CI)

OR (95% CI)

HADS-A ≥ 8 n = 2891

Diuretics

1.12 (1.03; 1.23)*

1.18 (1.07; 1.31)*

1.14 (1.02; 1.28)*

Lipid-lowering agents

1.17 (1.06; 1.30)*

1.27 (1.12; 1.44)*

1.19 (1.05; 1.36)*

Aspirin

1.11 (1.01; 1.23)*

1.16 (1.03; 1.30)*

1.10 (0.96; 1.25)

Anticoagulants

0.93 (0.79; 1.11)

1.19 (0.99; 1.44)

0.93 (0.75; 1.14)

Aldosterone antagonists

1.04 (0.93; 1.16)

1.02 (0.90; 1.16)

0.91 (0.79; 1.04)

Nitrates

1.29 (1.18; 1.41)*

1.30 (1.17; 1.44)*

1.26 (1.13; 1.40)*

Antiarrhythmics

1.13 (1.01; 1.28)*

1.27 (1.12; 1.44)*

1.25 (1.10; 1.43)*

Digoxin

1.05 (0.93; 1.20)

1.13 (0.98; 1.29)

1.10 (0.95; 1.26)

Angiotensin receptor antagonists

1.06 (0.96; 1.18)

1.08 (0.97; 1.20)

1.04 (0.98; 1.16)

ACE-inhibitors

0.99 (0.91; 1.08)

1.02 (0.93; 1.12)

0.98 (0.88; 1.08)

Beta-blockers

1.16 (1.04; 1.31)*

1.23 (1.09; 1.39)*

1.14 (1.01; 1.29)*

  1. *Statistically significant association
  2. aMultivariable logistic regression model unadjusted
  3. bMultivariable logistic regression model adjusted for age, sex, TU-comorbidity index score and diagnostic group
  4. cMultivariable logistic regression model adjusted for age, sex, TU-comorbidity index score, diagnostic group, cardiac drug group and psychotropic medication