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Table 3 ROC analysis for biomarker accuracy testing of circulating miRNAs under study

From: Identification of a circulating microRNAs biomarker panel for non-invasive diagnosis of coronary artery disease: case–control study

miRNA AUC
Area SEa Asymptotic Sig.b Asymptotic 95% CI
Lower Upper
miR-145 0.959 0.023 < 0.001*** 0.913 1.000
miR-182 0.959 0.023 < 0.001*** 0.913 1.000
miR-205 0.836 0.043 < 0.001*** 0.751 0.921
miR-133a 0.863 0.040 < 0.001*** 0.784 0.942
miR-155 0.767 0.049 < 0.001*** 0.670 0.864
miR-126 0.767 0.049 < 0.001*** 0.670 0.864
miR-146A 0.767 0.049 < 0.001*** 0.670 0.864
miR-21 0.767 0.049 < 0.001*** 0.670 0.864
miR-200b 0.740 0.051 < 0.001*** 0.639 0.840
miR-135b 0.712 0.053 < 0.001*** 0.608 0.816
miR-196b 0.644 0.056 0.003** 0.534 0.754
miR-223 0.616 0.057 0.015* 0.505 0.728
miR-140b 0.589 0.058 0.063 ns 0.476 0.702
miR-208 0.616 0.057 0.015* 0.505 0.728
  1. AUC: 0.5 or less = no discrimination, 0.7–0.8 = acceptable discrimination, 0.8–0.9 = excellent discrimination, and more than 0.9 = outstanding discrimination
  2. Significant P-values are in bold
  3. Abbreviations: AUC Area under the curve, SE Standard error