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Table 3 ROC analysis for biomarker accuracy testing of circulating miRNAs under study

From: Identification of a circulating microRNAs biomarker panel for non-invasive diagnosis of coronary artery disease: case–control study

miRNA

AUC

Area

SEa

Asymptotic Sig.b

Asymptotic 95% CI

Lower

Upper

miR-145

0.959

0.023

< 0.001***

0.913

1.000

miR-182

0.959

0.023

< 0.001***

0.913

1.000

miR-205

0.836

0.043

< 0.001***

0.751

0.921

miR-133a

0.863

0.040

< 0.001***

0.784

0.942

miR-155

0.767

0.049

< 0.001***

0.670

0.864

miR-126

0.767

0.049

< 0.001***

0.670

0.864

miR-146A

0.767

0.049

< 0.001***

0.670

0.864

miR-21

0.767

0.049

< 0.001***

0.670

0.864

miR-200b

0.740

0.051

< 0.001***

0.639

0.840

miR-135b

0.712

0.053

< 0.001***

0.608

0.816

miR-196b

0.644

0.056

0.003**

0.534

0.754

miR-223

0.616

0.057

0.015*

0.505

0.728

miR-140b

0.589

0.058

0.063 ns

0.476

0.702

miR-208

0.616

0.057

0.015*

0.505

0.728

  1. AUC: 0.5 or less = no discrimination, 0.7–0.8 = acceptable discrimination, 0.8–0.9 = excellent discrimination, and more than 0.9 = outstanding discrimination
  2. Significant P-values are in bold
  3. Abbreviations: AUC Area under the curve, SE Standard error
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BMC Cardiovascular Disorders

ISSN: 1471-2261

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