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Table 3 (A) Logistic regression analyses to determine risk factors for poor collateralization according to the Rentrop classification in diabetic patients; (B) logistic regression analyses to determine risk factors for poor collateralization according to the Werner classification in diabetic patients

From: High serum levels of N-epsilon-carboxymethyllysine are associated with poor coronary collateralization in type 2 diabetic patients with chronic total occlusion of coronary artery

 

Variables

OR (95% CI)

P value

(A)

   

Model 1

Male

0.816 (0.375–1.777)

0.609

Nagelkerke R2 = 0.303

Age per 10 years

1.099 (0.816–1.478)

0.535

Hosmer–Lemeshow test:

BMI

1.070 (0.976–1.174)

0.149

P = 0.651

Hypertension

0.422 (0.217–0.821)

0.011

 

Smoking

2.249 (1.189–4.255)

0.013

 

HbA1c

1.324 (1.084–1.619)

0.006

 

Hypercholesterolemia

1.527 (0.603–3.865)

0.372

 

Total-to-HDL cholesterol ratio

0.888 (0.696–1.134)

0.343

 

eGFR

0.967 (0.951–0.983)

 < 0.001

 

Log hsCRP

1.134 (1.003–1.282)

0.045

Model 2

Male

0.742 (0.310–1.775)

0.503

Nagelkerke R2 = 0.430

Age per 10 years

1.124 (0.821–1.539)

0.465

Hosmer–Lemeshow test:

BMI

1.058 (0.959–1.167)

0.261

P = 0.981

Hypertension

0.323 (0.154–0.677)

0.003

 

Smoking

1.910 (0.973–3.750)

0.06

 

HbA1c

1.309 (1.057–1.620)

0.014

 

Hypercholesterolemia

1.276 (0.494–3.296)

0.615

 

Total-to-HDL cholesterol ratio

0.864 (0.658–1.135)

0.294

 

eGFR

0.964 (0.947–0.981)

 < 0.001

 

Log hsCRP

1.182 (1.032–1.355)

0.016

 

Log2 CML

1.999 (1.530–2.613)

 < 0.001

(B)

Model 3

Male

0.874 (0.291–2.628)

0.810

Nagelkerke R2 = 0.306

Age per 10 years

0.919 (0.620–1.363)

0.675

Hosmer–Lemeshow test:

BMI

0.977 (0.872–1.095)

0.693

P = 0.911

Hypertension

0.442 (0.181–1.082)

0.074

 

Smoking

4.514 (1.707–11.935)

0.002

 

HbA1c

1.351 (1.027–1.778)

0.032

 

Hypercholesterolemia

0.851 (0.223–3.241)

0.813

 

Total-to-HDL cholesterol ratio

1.489 (1.056–2.098)

0.023

 

eGFR

0.970 (0.948–0.993)

0.012

 

Log hsCRP

1.248 (1.047–1.487)

0.013

Model 4

Male

0.662 (0.209–2.091)

0.482

Nagelkerke R2 = 0.398

Age per 10 years

0.910 (0.599–1.383)

0.659

Hosmer–Lemeshow test:

BMI

0.955 (0.845–1.080)

0.465

P = 0.456

Hypertension

0.379 (0.146–0.984)

0.046

 

Smoking

3.736 (1.375–10.150)

0.010

 

HbA1c

1.293 (0.983–1.702)

0.067

 

Hypercholesterolemia

0.587 (0.144–2.391)

0.457

 

Total-to-HDL cholesterol ratio

1.538 (1.052–2.249)

0.026

 

eGFR

0.973 (0.950–0.996)

0.021

 

Log hsCRP

1.290 (1.076–1.547)

0.006

 

Log2 CML

1.827 (1.361–2.453)

 < 0.001

  1. Model 1 and 3, adjusted for conventional cardiovascular factors; Model 2 and 4, adjusted for the factors included in Model 1 and 3 with the addition of CML; P values were in bold if P < 0.05
  2. BMI body mass index, HbA1c glycosylated hemoglobin A1c, HDL high-density lipoprotein, eGFR estimated glomerular filtration rate, hsCRP high sensitive C reactive protein