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Table 1 (A) Characteristics and parameters of patients categorized by the Rentrop classification; (B) characteristics and parameters of patients categorized by the Werner classification

From: High serum levels of N-epsilon-carboxymethyllysine are associated with poor coronary collateralization in type 2 diabetic patients with chronic total occlusion of coronary artery

(A)

 

Poor CCV

(n = 107)

Good CCV

(n = 135)

P value

Male, n (%)

74 (69.16)

114 (84.44)

0.005

Age, years

67.31 ± 11.22

64.19 ± 10.10

0.024

BMI, kg/m2

25.25 ± 3.74

24.98 ± 3.34

0.546

Smoking, n (%)

41 (38.32)

34 (25.19)

0.036

Hypertension, n (%)

71 (66.36)

106 (78.52)

0.041

SBP, mmHg

134.93 ± 21.58

136.06 ± 19.96

0.672

DBP, mmHg

73.45 ± 10.55

75.11 ± 11.43

0.246

FBG, mmol/L

8.44 ± 3.41

7.69 ± 2.77

0.060

HbA1c, %

6.95 ± 1.43

6.37 ± 1.58

0.003

Dyslipidemia, n (%)

29 (27.10)

22 (16.30)

0.056

Triglyceride, mmol/L

1.77 ± 0.93

1.70 ± 1.22

0.650

Total cholesterol, mmol/L

3.98 ± 1.29

3.87 ± 1.08

0.496

LDL-C, mmol/L

2.33 ± 1.05

2.25 ± 0.89

0.516

HDL-C, mmol/L

1.01 ± 0.20

1.06 ± 0.28

0.133

ApoA, g/L

1.12 ± 0.22

1.15 ± 0.23

0.312

ApoB, g/L

0.80 ± 0.27

0.77 ± 0.23

0.367

Lp(a), g/L

0.36 ± 0.86

0.30 ± 0.29

0.411

BUN, mmol/L

7.18 ± 4.84

6.93 ± 3.77

0.648

Serum creatinine, μmol/L

101.74 ± 53.74

85.10 ± 66.51

0.037

eGFR, ml·min−1·1.73 m−2

68.51 ± 20.80

85.17 ± 20.49

 < 0.001

UA, μmol/L

348.69 ± 104.15

338.62 ± 97.02

0.438

hsCRP, mg/L

14.58 ± 33.21

7.14 ± 20.63

0.034

Medication, n (%)

ACE inhibitor/ARB

59 (55.14)

61 (45.19)

0.124

β-blocker

81 (75.70)

90 (66.67)

0.125

Nitrate

45 (42.06)

53 (39.26)

0.660

Calcium channel blocker

20 (18.69)

24 (17.78)

0.855

Statins

80 (74.77)

105 (77.78)

0.583

Antidiabetic therapy

107 (100.00)

135 (100.00)

/

(B)

 

Poor CCV

(n = 193)

Good CCV

(n = 49)

P value

Male, n (%)

145 (75.13)

43 (87.76)

0.082

Age, years

65.96 ± 11.03

64.04 ± 9.23

0.263

BMI, kg/m2

25.04 ± 3.56

25.35 ± 3.34

0.575

Smoking, n (%)

69 (35.75)

6 (12.24)

0.002

Hypertension, n (%)

137 (70.98)

40 (81.63)

0.152

SBP, mmHg

135.80 ± 21.01

134.59 ± 19.38

0.715

DBP, mmHg

74.19 ± 10.90

75.10 ± 11.75

0.608

FBG, mmol/L

8.03 ± 3.20

7.71 ± 2.43

0.509

HbA1c, %

6.76 ± 1.55

6.10 ± 1.37

0.007

Dyslipidemia, n (%)

45 (23.32)

6 (12.24)

0.116

Triglyceride, mmol/L

1.74 ± 0.97

1.72 ± 1.52

0.912

Total cholesterol, mmol/L

3.98 ± 1.24

3.68 ± 0.89

0.112

LDL-C, mmol/L

2.35 ± 1.01

2.04 ± 0.69

0.048

HDL-C, mmol/L

1.02 ± 0.24

1.09 ± 0.27

0.080

ApoA, g/L

1.13 ± 0.22

1.17 ± 0.23

0.187

ApoB, g/L

0.80 ± 0.26

0.71 ± 0.18

0.022

Lp(a), g/L

0.34 ± 0.67

0.28 ± 0.32

0.547

BUN, mmol/L

7.10 ± 4.49

6.52 ± 1.89

0.377

Serum creatinine, μmol/L

96.90 ± 67.79

74.98 ± 17.30

0.026

eGFR, ml·min−1·1.73 m−2

75.04 ± 22.85

88.68 ± 15.23

 < 0.001

UA, μmol/L

346.85 ± 102.83

327.98 ± 78.58

0.232

hsCRP, mg/L

11.73 ± 29.00

5.32 ± 17.18

0.140

Medication, n (%)

ACE inhibitor/ARB

99 (51.30)

21 (42.86)

0.338

β-blocker

141 (73.06)

30 (61.22)

0.116

Nitrate

76 (39.38)

22 (44.90)

0.517

Calcium channel blocker

36 (18.65)

8 (16.33)

0.837

Statins

144 (74.61)

41 (83.67)

0.257

Antidiabetic therapy

193 (100.00)

49 (100.00)

/

  1. Data are mean ± SD or number (%); P values were in bold if P < 0.05
  2. CCV coronary collateral vessel, BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, FBG fasting blood glucose, HbA1c glycosylated hemoglobin A1c, LDL-C low-density lipoprotein cholesterol, HDL-C high-density lipoprotein cholesterol, BUN blood urea nitrogen, UA uric acid, eGFR estimated glomerular filtration rate, hsCRP high-sensitivity C reactive protein