From: Non-invasive quantification of pressure–volume loops in patients with Fontan circulation
Mean (95%CI) | Fontan n = 17 | Fontan RV n = 9 | Fontan LV n = 8 | Controls n = 17 |
---|---|---|---|---|
Stroke work (J) | 0.66 (0.40–0.91) ** | 0.77 (0.35–1.20) * | 0.52 (0.16–0.88) *** | 1.15 (0.96–1.33) |
Stroke work/BSA (J/m2) | 0.46 (0.33–0.58) *** | 0.54 (0.34–0-74) * | 0.36 (0.20–0.52) **** | 0.70 (0.64–0.76) |
Potential energy (J) | 0.46 (0.31–0.62) | 0.55 (0.32–0.51) | 0.37 (0.15–0.59) | 0.40 (0.31–0.49) |
Potential energy/BSA (J/m2) | 0.34 (0.27–0.42) ** | 0.41 (0.30–0.51) ***† | 0.27 (0.18–0.37) | 0.24 (0.21–0.27) |
Ventricular efficiency (%) | 56 (52–60) **** | 56 (50–62) **** | 56 (48–63) **** | 75 (72–77) |
External power (J/s) | 0.83 (0.51–1.15) ** | 0.92 (0.45–1.40) * | 0.74 (0.18–1.29) ** | 1.45 (1.19–1.71) |
External power/BSA (J/s/m2) | 0.60 (0.46–0.74) ** | 0.68 (0.83–1.3) | 0.51 (0.30–0.71) ** | 0.89 (0.76–1.03) |
Contractility, Ees (mmHg/ml) | 1.2 (1.0–1.5) * | 1.07 (0.77–1.26) * | 1.46 (1.09–1.82) | 1.7 (1.3–2.1) |
Arterial elastance, Ea (mmHg/ml) | 2.0 (1.5–2.5) * | 1.7 (1.2–2.2) | 2.4 (1.3–3.4) ** | 1.3 (1.1–1,6) |
Ea/Ees | 1.5 (1.4–1.8) **** | 1.6 (1.3–1.9) **** | 1.6 (1.1–2.0) **** | 0.8 (0.7–0.9) |
Energy per ejected volume (mJ/ml) | 17 (15–19) | 17 (15–20) | 16 (12–19) | 17 (16–18) |