Table 3 Comparison of pro-inflammatory cytokine polymorphism between groups
Characteristics | With TGA n = 27 group 1 | Without TGA n = 27 group 2 | p-value |
|---|---|---|---|
IL-1α -889C/T (rs1800587) | 0.713* | ||
CC | 15 (55.6) | 12 (44.4) | |
CT | 8 (29.6) | 11 (40.7) | |
TT | 4 (14.8) | 4 (14.8) | |
C | 38 (70.4) | 35 (64.9) | |
T | 16 (29.6) | 19 (35.1) | |
IL-1β -511C > T (rs16944) | 0.831* | ||
CC | 10 (37) | 8 (29.6) | |
CT | 13 (48.1) | 14 (51.9) | |
TT | 4 (14.8) | 5 (18.5) | |
C | 33 (61.2) | 30 (55,6) | |
T | 21(38.8) | 24 (44.4) | |
TNFα -308G > A (rs1800629) | 0.553* | ||
AA | 0 (0) | 1 (3.7) | |
GA | 5 (18.5) | 6 (22.2) | |
GG | 22 (81.5) | 20 (74.1) | |
A | 5 (9.3) | 8 (14.9) | |
G | 49 (90.7) | 46 (85.1) | |
TNFα -238G > A (rs361525) | 0.999* | ||
AA | 0 (0) | 0 (0) | |
GA | 3 (11.1) | 3 (11.1) | |
GG | 24 (88.9) | 24 (88.9) | |
A | 3 (5,6) | 3 (5,6) | |
G | 51 (94.4) | 51 (94.4) | |
IL-6 -174G > C (rs1800795) | 0.999* | ||
GC | 8 (29.6) | 9 (33.3) | |
GG | 19 (70.4) | 18 (66.7) | |
CC | 0 (0) | 0 (0) | |
G | 46 (85.1) | 45 (83.3) | |
C | 8 (14.9) | 9 (16.7) | |
IL-6 -572G > C (rs1800796) | 0.999* | ||
GC | 6 (22.2) | 5 (18.5) | |
GG | 21 (77.8) | 22 (81.5) | |
CC | 0 (0) | 0 (0) | |
G | 48 (88.8) | 49 (90.7) | |
C | 6 (11.2) | 5 (9.3) | |