Table 2 The results of univariate analysis
From: Effect of CPB glucose levels on inflammatory response after pediatric cardiac surgery
Statistics | Effect size (β) | P-value | |
|---|---|---|---|
Age of surgery, month | 37.53 (18.91–69.83) | 1.01 (1.01, 1.01) | < 0.001 |
Age category of surgery | 0.018 | ||
Infants | 2127 (28.94%) | 1.0 | |
Toddlers and preschoolers | 3526 (47.97%) | 1.37 (1.17, 1.61) | < 0.0001 |
School age | 1415 (19.25%) | 8.63 (7.30, 10.20) | < 0.0001 |
Teenagers | 282 (3.84%) | 0.85 (0.56, 1.27) | 0.4169 |
Gender | |||
Female | 3895 (52.99%) | 1.0 | |
Male | 3455 (47.01%) | 1.01 (0.91, 1.13) | 0.8256 |
Surgery year | |||
2012–2014 | 2713 (36.91%) | 1.0 | |
2015–2017 | 2527 (34.38%) | 0.98 (0.86, 1.11) | 0.7312 |
2018–2020 | 2110 (28.71%) | 0.63 (0.54, 0.72) | < 0.0001 |
Body surface area, m2 | 0.59 (0.47–0.75) | 4.26 (3.51, 5.17) | < 0.001 |
BMI, kg/m2 | 15.19 (14.07–16.53) | 1.01 (0.99, 1.04) | 0.3206 |
Preoperative hemoglobin | 128.00 (119.00–136.00) | 1.02 (1.02, 1.02) | < 0.0001 |
Residence altitude | |||
Low altitude | 5038 (68.54%) | 1.0 | |
High altitude | 2312 (31.46%) | 1.07 (0.95, 1.20) | 0.2811 |
Hemodynamic pathology | |||
Non cyanotic | 6262 (85.20%) | 1.0 | |
Cyanotic | 1088 (14.80%) | 1.63 (1.41, 1.88) | < 0.0001 |
Extracardiac malformations | |||
Absence | 7053 (95.96%) | 1.0 | |
Presence | 297 (4.04%) | 1.09 (0.83, 1.44) | 0.5328 |
Genetic anomalies | |||
Non | 6964 (94.74%) | 1.0 | |
Presence | 386 (5.13%) | 0.92 (0.71, 1.19) | 0.5242 |
Clinical pathway implementation | |||
Non | 1299 (17.67%) | 1.0 | |
Presence | 6051 (82.33%) | 0.66 (0.57, 0.75) | < 0.0001 |
PAH | |||
Non | 4585 (62.38%) | 1.0 | |
Presence | 2765 (37.62%) | 0.70 (0.62, 0.78) | < 0.0001 |
Aorta crossclamp time, min | 34.00 (23.00–52.00) | 1.01 (1.01, 1.01) | < 0.001 |
Red cell need, U | 1.00 (0.00–2.00) | 0.93 (0.88, 0.99) | 0.0157 |
Steroids need | < 0.001 | ||
No | 7052 (95.95%) | 1.0 | |
Yes | 298 (4.05%) | 1.81 (1.41, 2.32) | < 0.0001 |
Glucose infusion | |||
No | 7179 (97.67%) | 1.0 | |
Yes | 171 (2.33%) | 0.96 (0.66, 1.39) | 0.8184 |
Insulin need | |||
No | 6712 (91.32%) | 1.0 | |
Yes | 638 (8.68%) | 9.33 (7.82, 11.12) | < 0.0001 |
Aristotle complexity score | 6.00 (6.00–7.00) | 1.13 (1.09, 1.18) | < 0.0001 |
Aristotle complexity level | |||
Level 1 | 1197 (16.29% | 1.0 | |
Level 2 | 5020 (68.30%) | 1.24 (1.05, 1.46) | 0.0096 |
Level 3 | 1005 (13.67%) | 1.78 (1.45, 2.18) | < 0.0001 |
Level 4 | 128 (1.74%) | 3.18 (2.17, 4.66) | < 0.0001 |
Glucose, mmol/L | 6.40 (5.30–7.80) | 1.32 (1.29, 1.35) | < 0.001 |