Table 1 Demographic and baseline characteristics of patients with HF hospitalization
Characteristics | T2DM | AF | ||||
|---|---|---|---|---|---|---|
Overall | Recurrent HF Hospitalizations | Overall | Recurrent HF Hospitalizations | |||
None | ≥ 1 | None | ≥ 1 | |||
N | 2344 | 1573 | 771 | 4585 | 3294 | 1291 |
Age at index (Mean [SD]) | 76.4 (10.32) | 76.7 (10.4) | 75.8 (10.0) | 79.6 (10.3) | 78.8 (10.3) | 79.9 (10.4) |
Gender, Male (%) | 59.1 | 58.7 | 59.9 | 54.2 | 55.2 | 53.9 |
Any CRT devices prior to index (%) | 15.4 | 14# | 18.2# | 16.9 | 15.3# | 20.8# |
Follow-up time (Patient years) | 4268.5 | 2514.2 | 1753.3 | 7845.6 | 5142 | 2703.6 |
Smoking status (%) | ||||||
Current smoker | 11.9 | 12.5 | 10.5 | 9.8 | 9.8 | 9.8 |
Never smoker | 41.5 | 41.0 | 42.4 | 41.4 | 41.2 | 41.9 |
Former smoker | 44.8 | 44.6 | 45.1 | 41.6 | 41.3 | 42.2 |
Missing/unknown | 1.9 | 1.9 | 1.9 | 7.3 | 7.7 | 6.1 |
BMI (Mean [SD])* | 30.9 (7.0) | 30.8 (7.1) | 31.1(6.9) | 28.5(6.8) | 28.3(6.9) | 28.9(6.5) |
Underweight: < 18.5 kg/m2 (%) | 0.9 | 0.9 | 1.0 | 1.5 | 1.6 | 1.1 |
Normal weight: > = 18.5 and < 25 kg/m2 (%) | 14.6 | 15.1 | 13.6 | 16.9 | 16.8 | 17.1 |
Overweight: > = 25 and < 30 kg/m2 (%) | 23 | 23 | 23 | 17.2 | 16.6 | 18.8 |
Obese: > = 30 kg/m2 (%) | 40.7 | 39.7 | 42.7 | 20.2 | 19.1 | 23.1 |
Missing/Unknown (%) | 20.8 | 21.4 | 19.7 | 44.2 | 45.8 | 40.0 |
Comorbidities (%)* | ||||||
AF | 49.9 | 49.1 | 51.5 | 100 | 100 | 100 |
Anemia | 25.2 | 24.5 | 26.6 | 20.2 | 19.4# | 22.2# |
Angina pectoris | 28.7 | 27.3 | 31.7 | 23.4 | 22.8 | 25.1 |
Dyslipidemia | 30.5 | 30.3 | 30.9 | 19.8 | 18.8# | 22.3# |
Hypertension | 76.5 | 76.0 | 77.4 | 68.0 | 67.0# | 70.6# |
Oedema | 23.9 | 24.9 | 21.9 | 23.3 | 24.0 | 21.5 |
Chronic pulmonary disorder | 31.5 | 31.7 | 31.1 | 27.5 | 26.9 | 28.9 |
Diabetes | 100 | 100 | 100 | 26.2 | 24.1# | 31.3# |
Myocardial infarction | 21.2 | 20.9 | 21.9 | 16.4 | 16.2 | 16.8 |
Renal disease | 38.1 | 37.5 | 39.4 | 30.1 | 29.7 | 31.2 |
Pneumonia | 16.3 | 16.5 | 16.1 | 17.6 | 18.4# | 15.7# |
Ischaemic heart disease | 58.2 | 57.1 | 60.3 | 47.3 | 46.2 | 50.1 |
Any concomitant medications at index (%) | 85.7 | 84.8 | 87.4 | 82.5 | 81.3 | 85.6 |
ACEi | 53.1 | 53.2 | 52.9 | 47.6 | 46.5 | 50.4 |
ARB | 23.7 | 22.5# | 26.2# | 19.0 | 17.9# | 21.7# |
ACEi/ARB | 74.2 | 73.1 | 76.4 | 65.0 | 63.1# | 70.1# |
Beta-blockers | 53.5 | 52.4 | 55.6 | 55.4 | 54.7 | 57.2 |
MRA | 19.2 | 17.3# | 23# | 18.8 | 17.5# | 22.3# |
eGFR (Mean [SD])* | 61.5(25.9) | 62(25.3) | 60.4 (25) | 63.6 (24.2) | 64.2(24.2) # | 62.2 (24.0) |
eGFR > = 60 ml/min/1.73 m2 | 47.7 | 48.6 | 45.9 | 49.1 | 50.1 | 46.9 |
eGFR < 60 ml/min/1.73 m2 | 47.8 | 46.5 | 50.3 | 40.7 | 39.3 | 44.4 |
Missing/unknown | 4.9 | 4.8 | 3.8 | 10.1 | 10.7 | 8.8 |