Table 1 Baseline characteristics
Total/mean ± SD | Invasive coronary angiography (QCA) | p value | ||
|---|---|---|---|---|
No obstructive CAD | Obstructive CAD | |||
Number of patients | 100 | 70 | 30 | |
Female gender | 70 | 50 (71.4%) | 20 (66.7%) | 0.812 |
BMI (kg/m2) | 25.5 ± 5.6 | 24.9 ± 5.4 | 25.1 ± 3.7 | 0.116 |
Age (years) | 82.3 ± 6.5 | 81.6 ± 6.7 | 83.8 ± 5.8 | 0.254 |
Arterial hypertension | 84 | 56 (80.0%) | 28 (93.3%) | 0.138 |
Diabetes mellitus | 20 | 15 (21.4%) | 5 (16.7%) | 0.786 |
Peripheral artery disease | 5 | 5 (7.2%) | 0 (0%) | 0.318 |
Stroke/TIA | 15 | 7 (9.1%) | 8 (24.2%) | 1.000 |
Pacemaker | 3 | 2 (2.9%) | 1 (3.3%) | 1.000 |
Atrial fibrillation | 14 | 9 (12.9%) | 5 (16.7%) | 0.754 |
Hemoglobin (g/l) | 114.7 ± 17.8 | 116.9 ± 17.8 | 109.6 ± 17.0 | 0.120 |
COPD | 6 | 6 (8.6%) | 0 (0%) | 0.174 |
GFR (Cockcroft Gault; ml/min/1.73 m2) | 52.0 ± 21.8 | 53.9 ± 22.6 | 47.5 ± 19.3 | 0.218 |
STS score | 4.6 ± 2.9 | 4.2 ± 2.6 | 5.2 ± 3.0 | 0.080 |
Aortic valve area (cm2) | 0.60 ± 0.23 | 0.61 ± 0.22 | 0.58 ± 0.27 | 0.420 |
Mean aortic gradient (mmHg) | 41 ± 16 | 40 ± 17 | 43 ± 14 | 0.336 |
LVEF (%) | 57 ± 13 | 56 ± 13 | 58 ± 12 | 0.319 |
Reduced LVEF < 45% | 17 | 14 (20.0%) | 3 (10.0%) | 0.262 |
Total CACS (Median IQR [25–75]) | 564 [160–1045] | 386 [75–765] | 1019 [542–1907] | 0.001 |