Fig. 1
From: H3K9me2 regulation of BDNF expression via G9a partakes in the progression of heart failure
G9a is upregulated in both HF patients and OGD-treated cell models. A A total of 487 differentially expressed genes by screening in the GSE120895 dataset. B Heatmap analysis of the top 20 significantly differentially expressed mRNAs. C RT-qPCR analysis of G9a mRNA expression in collected HF patient sera (n = 40) and healthy subject sera (n = 40). D, E Expression of G9a in OGD-treated cell models and controls detected by RT-qPCR (D) and Western blot (E) (Uncropped protein blots are provided in the Additional file 1). Data are expressed as mean ± SD. Each experiment was repeated at least three times. A comparison of data from 2 groups was performed by an unpaired t test. **p < 0.01