The correlation between lipoprotein(a) elevations and the risk of recurrent cardiovascular events in CAD patients with different LDL-C levels

Table 4 Univariate and multivariate analysis of correlation between Lp(a) elevations and endpoint events in different subgroups

Endpoint events	Group	Unadjusted		Adjusted*
Endpoint events	Group	P	HR (95%CI)	P	HR (95%CI)
MACE	S0	0.004	1.74 (1.20–2.53)	0.012	1.63 (1.12–2.38)
	S1	0.045	1.73 (1.01–2.95)	0.076	1.62 (0.95–2.77)
	S2	0.007	2.65 (1.31–5.36)	0.007	2.65 (1.31–5.36)
	S3	0.312	0.58 (0.20–1.67)	0.186	0.49 (0.17–1.42)
	S2 + S3	0.121	1.53 (0.89–2.62)	0.172	1.46 (0.85–2.51)
ACE	S0	0.006	2.00 (1.22–3.28)	0.037	1.70 (1.03–2.81)
	S1	0.036	2.10 (1.05–4.21)	0.019	2.33 (1.15–4.72)
	S2	0.101	2.22 (0.86–5.76)	0.152	2.01 (0.77–5.23)
	S3	0.869	0.90 (0.25–3.19)	0.570	0.68 (0.18–2.61)
	S2 + S3	0.203	1.61 (0.77–3.33)	0.232	1.56 (0.75–3.24)

S0: the entire sample; S1: LDL-C ≥ 1.8 mmol/L; S2: 1.4 ≤ LDL-C < 1.8 mmol/L; S3: LDL-C < 1.4 mmol/L; S2 + S3: LDL-C < 1.8 mmol/L
^*The variables with P < 0.05 in univariate analysis were included in multivariate COX regression analysis. The results of univariate analysis are listed in Additional file 1: Table S1

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