Table 2 Distribution of MALAT1 gene rs3200401 among total participants, control participants and MI patients
From: Long noncoding RNA MALAT1 polymorphism predicts MACCEs in patients with myocardial infarction
|  | Total (n = 1224) | Controls (n = 729) | MI patients (n = 495) | ||||||
|---|---|---|---|---|---|---|---|---|---|
nonMACCE (n = 1050) | MACCE (n = 174) | P value | nonMACCE (n = 678) | MACCE (n = 51) | P value | nonMACCE (n = 372) | MACCE (n = 123) | P value | |
rs3200401 Genotype | Â | Â | Â | Â | Â | Â | Â | Â | Â |
C/C | 755 (71.9%) | 109 (62.6%) | Â | 479 (70.6%) | 35 (68.6%) | Â | 276 (74.2%) | 74 (60.2%) | Â |
C/T | 268 (25.5%) | 62 (35.6%) | Â | 181 (26.7%) | 15 (29.4%) | Â | 87 (23.4%) | 47 (38.2%) | Â |
T/T | 27 (2.6%) | 3 (1.7%) | 0.020 | 18 (2.7%) | 1 (2.0%) | 0.885 | 9 (2.4%) | 2 (1.6%) | 0.006 |
Allele | Â | Â | Â | Â | Â | Â | Â | Â | Â |
C | 1778 (84.7%) | 280 (80.5%) | Â | 1139 (84.0%) | 85 (83.3%) | Â | 639 (85.9%) | 195 (79.3%) | Â |
T | 322 (15.3%) | 68 (19.5%) | 0.047 | 217 (16.0%) | 17 (16.7%) | 0.860 | 105 (14.1%) | 51 (20.7%) | 0.014 |
Dominant model | Â | Â | Â | Â | Â | Â | Â | Â | Â |
CC | 755 (71.9%) | 109 (62.6%) | Â | 479 (70.7%) | 35 (68.6%) | Â | 276 (74.2%) | 75 (60.5%) | Â |
CT + TT | 295 (28.1%) | 65 (37.4%) | 0.013 | 199 (29.4%) | 16 (31.4%) | 0.760 | 96 (25.8%) | 49 (39.5%) | 0.003 |
Overdominant model | Â | Â | Â | Â | Â | Â | Â | Â | Â |
CT | 268 (25.5%) | 62 (35.6%) | Â | 181 ( 26.7%) | 15 (29.4%) | Â | 87 (23.4%) | 47 (38.2%) | Â |
CC + TT | 782 (74.5%) | 112 (64.4%) | 0.005 | 497 (73.3%) | 36 (70.6%) | 0.673 | 285 (76.6%) | 76 (61.8%) | 0.001 |
Recessive model | Â | Â | Â | Â | Â | Â | Â | Â | Â |
TT | 27 (2.6%) | 3 (1.7%) | Â | 18 (2.7%) | 1 (2.0%) | Â | 9 (2.4%) | 2 (1.5%) | Â |
CC + CT | 1023 (97.4%) | 171 (98.3%) | 0.790 | 660 (97.4%) | 50 (98.0%) | > 0.999 | 363 (97.6%) | 130 (98.5%) | > 0.999 |