Association of latent class analysis-derived subphenotypes of acute kidney injury with mortality in critically ill patients with cardiovascular disease: a retrospective cohort study

Table 3 Association of disease severity score and outcomes with LCA-derived AKI classes

	Class 1	Class 2	Class 3	Class 4	p
SAPS II score	37.14 ± 11.85	35.08 ± 13.08	35.66 ± 13.10	48.81 ± 14.03	< 0.001
SOFA score	5.00 (3.00–7.00)	5.00 (3.00–7.00)	3.00 (2.00–5.00)	6.00 (5.00–9.00)	< 0.001
Elixhauser comorbidity score	0.00 (0.00–5.00)	1.00 (0.00–6.00)	3.00 (0.00–8.00)	7.00 (3.00–12.00)	< 0.001
Length of ICU stay, days	2.23 (1.29–3.92)	2.27 (1.32–4.38)	3.02 (1.90–5.68)	4.07 (2.16–7.33)	< 0.001
28-day mortality	52 (1.6)	66 (4.7)	375 (15.2)	138 (25.1)	< 0.001

Continuous variables are presented as the SEM ± SD or median (interquartile range), as appropriate. Categorical variables are presented as numbers (percentages). The chi-square test of categorical variables and analysis of variance or the Kruskal–Wallis test of continuous variables were used for comparisons among groups. AKI, acute kidney injury; LCA, latent class analysis; SAPS II, Simplified Acute Physiology Score II; SOFA, Sequential Organ Failure Assessment

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