Skip to main content

Table 2 Frequencies of ALDH2 rs671, MTHFR rs1801133 genotypes and alleles in hypertensive patients and controls

From: Association of ALDH2 rs671 and MTHFR rs1801133 polymorphisms with hypertension among Hakka people in Southern China

Genotype/allele

Hypertensive patients (n = 3057)

Controls (n = 2215)

χ2

P value

ALDH2 rs671

    

 G/G

1442 (47.17%)

1029 (46.46%)

2.844

0.242

 G/A

1358 (44.42%)

970 (43.79%)

  

 A/A

257 (8.41%)

216 (9.75%)

  

 G

4242 (69.38%)

3028 (68.35%)

1.272

0.259

 A

1872 (30.62%)

1402 (31.65%)

  

 HWE (χ2, P)

χ2 = 3.253, P = 0.197

χ2 = 0.174, P = 0.917

  

MTHFR rs1801133

    

 C/C

1555 (50.87%)

1264 (57.07%)

19.842

< 0.001

 C/T

1287 (42.10%)

816 (36.84%)

  

 T/T

215 (7.03%)

135 (6.09%)

  

 C

4397 (71.92%)

3344 (75.49%)

16.760

< 0.001

 T

1717 (28.08%)

1086 (24.51%)

  

 HWE (χ2, P)

χ2 = 2.770, P = 0.250

χ2 = 0.026, P = 0.987

  
  1. The bold values indicate P < 0.05, with statistically significant difference
  2. HWE, Hardy Weinberg Equilibrium