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Table 4 Temporal trends in in-hospital and 1-year-outcomes in patients with advanced CKD (G3b-G5)

From: Temporal trends in treatment strategies and clinical outcomes among patients with advanced chronic kidney disease and ST-elevation myocardial infarctions: results from the Bremen STEMI registry

  Time period
T1 2006–2010 (n = 407) T2 2011–2015 (n = 313) T3 2016–2019 (n = 298) Significance
In hospital events
 Resuscitations (%) 6.9 8.9 13.1 < 0.01
 Cerebrovascular events/TIA (%) 0.5 0.9 1.0 0.58
 TIMI minimal bleedings (%) 10.7 10.8 21.1 < 0.01
 TIMI minor bleedings (%) 3.2 1.6 2.7 0.49
 TIMI major bleedings (%) 2.2 1.9 6.7 < 0.01
 Overall mortality (%) 26.6 29.3 30.6 0.18
 Acute kidney injury (KDIGO stage 1 + (%)) 38.3 44.8 41.6 0.47
Adverse events at 1 year
 In-stent-thrombosis (ST) (%) 3.0 1.3 1.0 0.047
 Myocardial re-infarction (AMI) (%) 7.1 5.4 3.1 < 0.01
 Repeat target lesion revascularisation (TLR) (%) 3.3 0.3 1.5 0.04
Cumulative isch. events (ST + AMI + TLR) (%) 10.8 5.7 3.1 < 0.01
Cerebrovascular events/TIA (%) 3.0 3.3 2.7 0.74
Overall mortality (%) 46.9 47.7 51.5 0.29
Bleeding events after hospital discharge (%) 2.0 6.0 5.5 0.044
Cumulative bleeding events (TIMI minor + major + any bleeding event after discharge.) (%) 6.9 8.9 13.4 < 0.01
Adverse events at 5 years
 Overall mortality (%) 67.2 66.4 0.72