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Table 2 In hospital and 1-year outcomes by CKD-stage

From: Temporal trends in treatment strategies and clinical outcomes among patients with advanced chronic kidney disease and ST-elevation myocardial infarctions: results from the Bremen STEMI registry

 

CKD stage

G1 (n = 3370)

G2 (n = 4005)

G3a (n = 1212)

G3b-G5 (n = 1018)

Significance

In hospital events

 Resuscitations (%)

1.9

3.3

6.9

9.3

< 0.01

 Cerebrovascular events/TIA (%)

0.2

0.6

1.1

0.8

< 0.01

 TIMI minimal bleedings (%)

6.2

7.7

11.4

13.8

< 0.01

 TIMI minor bleedings (%)

0.9

1.5

2.3

2.6

< 0.01

 TIMI major bleedings (%)

0.7

1.5

2.9

3.5

< 0.01

 Overall in-hospital mortality (%)

1.3

4.9

14.9

28.4

< 0.01

 Acute kidney injury KDIGO stg. 1 + (%)

8.4

12.8

28.4

41.9

< 0.01

  AKI requiring temporal renal replacement therapy (%)

0.4

0.9

3.1

5.0

< 0.01

  AKI requiring permanent renal replacement therapy (%)

0

0.04

0

2.5

< 0.01

Adverse events at 1 year

 Stent-thrombosis (ST) (%)

1.3

1.5

1.9

1.7

0.19

 Myocardial re-infarction (AMI) (%)

3.7

4.3

4.3

5.5

0.03

 Repeat target lesion revascularisation (TLR) (%)

2.1

2.3

1.6

1.3

0.41

Cumulative ischemic events (ST + AMI + TLR) (%)

5.1

6.3

5.8

6.5

0.12

 Cerebrovascular events/TIA (%)

0.9

1.8

1.9

3.0

< 0.01

 Overall mortality (%)

3.6

11.2

27.9

44.4

< 0.01

 Bleeding events after hospital discharge (%)

2.2

2.7

3.4

4.1

< 0.01

Cumulative bleeding events (TIMI min + major or any bleeding after disch.) (%)

3.7

5.4

8.2

9.4

< 0.01