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Table 2 In hospital and 1-year outcomes by CKD-stage

From: Temporal trends in treatment strategies and clinical outcomes among patients with advanced chronic kidney disease and ST-elevation myocardial infarctions: results from the Bremen STEMI registry

  CKD stage
G1 (n = 3370) G2 (n = 4005) G3a (n = 1212) G3b-G5 (n = 1018) Significance
In hospital events
 Resuscitations (%) 1.9 3.3 6.9 9.3 < 0.01
 Cerebrovascular events/TIA (%) 0.2 0.6 1.1 0.8 < 0.01
 TIMI minimal bleedings (%) 6.2 7.7 11.4 13.8 < 0.01
 TIMI minor bleedings (%) 0.9 1.5 2.3 2.6 < 0.01
 TIMI major bleedings (%) 0.7 1.5 2.9 3.5 < 0.01
 Overall in-hospital mortality (%) 1.3 4.9 14.9 28.4 < 0.01
 Acute kidney injury KDIGO stg. 1 + (%) 8.4 12.8 28.4 41.9 < 0.01
  AKI requiring temporal renal replacement therapy (%) 0.4 0.9 3.1 5.0 < 0.01
  AKI requiring permanent renal replacement therapy (%) 0 0.04 0 2.5 < 0.01
Adverse events at 1 year
 Stent-thrombosis (ST) (%) 1.3 1.5 1.9 1.7 0.19
 Myocardial re-infarction (AMI) (%) 3.7 4.3 4.3 5.5 0.03
 Repeat target lesion revascularisation (TLR) (%) 2.1 2.3 1.6 1.3 0.41
Cumulative ischemic events (ST + AMI + TLR) (%) 5.1 6.3 5.8 6.5 0.12
 Cerebrovascular events/TIA (%) 0.9 1.8 1.9 3.0 < 0.01
 Overall mortality (%) 3.6 11.2 27.9 44.4 < 0.01
 Bleeding events after hospital discharge (%) 2.2 2.7 3.4 4.1 < 0.01
Cumulative bleeding events (TIMI min + major or any bleeding after disch.) (%) 3.7 5.4 8.2 9.4 < 0.01