Table 1 Baseline characteristics by CKD-stage
| Â | CKD stage | ||||
|---|---|---|---|---|---|
G1 (n = 3370) | G2 (n = 4005) | G3a (n = 1212) | G3b-G5 (n = 1018) | Significance | |
Age (years ± SD) | 54.9 ± 10 | 66.1 ± 12 | 71,8 ± 11 | 75.9 ± 11 | < 0.01 |
Women (%) | 19.5 | 26.4 | 38.6 | 46.4 | < 0.01 |
Body mass index (BMI) (kg/m2 ± SD) | 27.7 ± 5 | 27.5 ± 5 | 27.5 ± 5 | 27.2 ± 5 | 0.01 |
Diabetes (%) | 16.2 | 17.6 | 24.9 | 29.8 | < 0.01 |
Current smokers (%) | 63.8 | 35.4 | 22.7 | 16.2 | < 0.01 |
Arterial hypertension (%) | 50.9 | 63.8 | 71.7 | 72.1 | < 0.01 |
Medical history | |||||
 PCI (%) | 9.4 | 12.8 | 15.5 | 14.8 | < 0.01 |
 Acute myocardial infarction (%) | 9.1 | 12.7 | 16.4 | 17.5 | < 0.01 |
 CABG (%) | 1.4 | 2.7 | 4.4 | 4.9 | < 0.01 |
 Stroke/TIA (%) | 3.0 | 5.9 | 8.4 | 10.1 | < 0.01 |
Treatment strategy | |||||
 Primary PCI (%) | 94.1 | 89.8 | 86.3 | 84.1 | < 0.01 |
 Urgent/early elect. CABG (%) | 3.0 | 5.3 | 7.4 | 7.5 | < 0.01 |
 Conservative (%) | 2.8 | 4.9 | 6.3 | 8.5 | < 0.01 |
Systemic thrombolysis with (rescue) PCI (%) | 1.1 | 2.1 | 4.5 | 4.2 | < 0.01 |
Systemic thrombolysis (stand alone) (%) | 0 | 0.15 | 0 | 0 | – |
Coronary vessels diseased | |||||
 1 (%) | 45.6 | 36.2 | 29.5 | 21.7 | < 0.01 |
 2 (%) | 30.6 | 31.2 | 32.4 | 29.8 | 0.05 |
 3 (%) | 23.7 | 32.6 | 38.1 | 48.5 | < 0.01 |
Subacute STEMI (%) | 11.1 | 12.6 | 12.4 | 13.8 | 0.02 |
Cardiogenic shock (%) | 6.4 | 10.4 | 23.7 | 30.9 | < 0.01 |
TIMI 0/1 flow after PCI (%) | 2.6 | 4.5 | 7.1 | 10.6 | < 0.01 |
Peak CK > 2000 U/l (%) | 31.9 | 31.4 | 30.5 | 28.8 | 0.07 |
Creatine at admission (mg/dl ± SD) | 0.75 ± 0.13 | 0.97 ± 0.15 | 1.23 ± 0.18 | 2.22 ± 4.15 | < 0.01 |
eGFR at admission (ml/min ± SD) | 101 ± 8.4 | 76.2 ± 8.6 | 53.2 ± 4.2 | 32.3 ± 10.0 | < 0.01 |
Contrast media used (ml ± SD) | 143.9 ± 61 | 146.5 ± 61 | 144.1 ± 63 | 144.6 ± 71 | 0.3 |
Contrast media > 150 ml (%) | 33.3 | 35.8 | 34.9 | 36.4 | 0.06 |
Stent type | |||||
 Bare metal stent (%) | 36.8 | 46.6 | 50.5 | 45.8 | < 0.01 |
 Drug eluting stent (%) | 59.3 | 47.5 | 41.1 | 44.1 | < 0.01 |
 No stent (POBA) (%) | 3.8 | 5.8 | 8.4 | 10.0 | < 0.01 |
Medication at discharge | |||||
 ASS (%) | 98.9 | 97.1 | 92.6 | 89.4 | < 0.01 |
 Clopidogrel (%) | 25.6 | 46.8 | 57.1 | 56.3 | < 0.01 |
 Ticagrelor or prasugrel (%) | 70.9 | 46.3 | 31.8 | 31.7 | < 0.01 |
 Triple therapy (%) | 8.4 | 12.2 | 16.2 | 12.6 | < 0.01 |
 Statin (%) | 95.5 | 89.2 | 78.3 | 68.1 | < 0.01 |
 ACE-inhibitor/ATR (%) | 90.3 | 82.1 | 70.4 | 55.8 | < 0.01 |
 Betablocker (%) | 77.8 | 80.4 | 75.7 | 64.5 | < 0.01 |