Use of levosimendan combined with Shenfu injection to treat acute heart failure patients with hypotension: a prospective randomized controlled single-blind study

Table 2 Comparison of hemodynamic parameters of the patients between levosimendan combined with Shenfu injection and levosimendan alone

	Levosimendan			P value	Levosimendan + SFI			P value	P value (SFI vs No)	P value (SFI vs No)
	Baseline	Post-2 h	Post-24 h	P value	Baseline	Post-2 h	Post-24 h	P value	P value (SFI vs No)	Baseline	Post-2 h	Post-24 h
HR (bpm)	74.0 (64.0, 82.0)	72.0 (67.0, 84.0)	74.5 (67.0, 84.0)	0.833	71.0 (60.0, 86.0)	69.5 (61.0, 81.0)	67.5 (61.0, 80.0)	0.927	0.525	0.265	0.210	0.042
CO (L/min)	1.9 (1.3, 2.6)	2.0 (1.5, 2.8)	2.2 (1.7, 3.0)	0.420	1.95 (1.3, 2.8)	2.45 (1.77, 3.45)	2.95 (2.1, 3.8)	0.001	< 0.001	0.676	0.084	0.019
CI (L/min/m²)	1.2 (0.74, 1.5)	1.3 (0.85, 1.5)	1.4 (0.86, 1.7)	0.347	1.1 (0.82, 1.6)	1.5 (1.15, 2.1)	1.88 (1.4, 2.4)	< 0.001	< 0.001	0.889	0.009	0.003
SVI (mL/beat)	15.0 (9.7, 23.0)	16.0 (10.5, 20.5)	16.5 (13.5, 23.0)	0.516	16.0 (11.0, 24.0)	20.0 (12.5, 30.5)	22.0 (19.0, 28.0)	0.004	< 0.001	0.501	0.024	0.003
SVRI (mmHg·min·mL⁻¹)	5633.0 (3969.0, 10,000.0)	5315.0 (3773.0, 8274.0)	4816.0 (3591.0, 6217.0)	0.214	6001.5 (3895.0, 8817.0)	5379.0 (3200.0, 7454.0)	4722.5 (3141.0, 6867.0)	0.250	0.076	0.763	0.320	0.705

All data are shown as median (IQR)
CO cardiac output, CI cardiac index, SVI stroke volume index, SVRI systemic vascular resistance index

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