Relationship of leisure-time and household physical activity level and type with cardiovascular disease: secondary analysis of the Takashima Study data

Table 3 Relationship between amount of leisure-time and household physical activity and onset of circulatory disease

	Men (n = 1343)									Women (n = 2,398)
	≤ 0.43 (METs-hr/day)		0.44–3.49 (METs-hr/day)			≥ 3.50 (METs-hr/day)				≤ 7.80 (METs-hr/day)		7.81–12.70 (METs-hr/day)			≥ 12.71 (METs-hr/day)
	n = 449		n = 447			n = 447			Trend test	n = 800		n = 805			n = 793			Trend test
			HR	95% CI	P-value	HR	95% CI	P value	P value			HR	95% CI	P value	HR	95% CI	P value	P value
CVD	21			14			19			16			14			8
Sex and age adjusted model	1.00	(Ref)	0.76	(0.39–1.50)	0.433	0.93	(0.50–1.73)	0.811	0.796	1.00	(Ref)	1.04	(0.50–2.12)	0.926	0.48	(0.21–1.12)	0.089	0.102
Multivariable adjusted model	1.00	(Ref)	0.85	(0.41–1.79)	0.670	0.64	(0.28–1.43)	0.273	0.275	1.00	(Ref)	0.83	(0.34–2.00)	0.677	0.09	(0.02–0.50)	0.006	0.010
Stroke	17			10			14			13			12			7
Sex and age adjusted model	1.00	(Ref)	0.67	(0.30–1.46)	0.313	0.87	(0.43–1.77)	0.699	0.671	1.00	(Ref)	1.10	(0.50–2.42)	0.812	0.52	(0.21–1.30)	0.159	0.178
Multivariable adjusted model	1.00	(Ref)	0.82	(0.35–1.92)	0.644	0.50	(0.19–1.31)	0.156	0.159	1.00	(Ref)	0.96	(0.38–2.46)	0.937	0.08	(0.01–0.54)	0.010	0.019

	Total(n = 3,741)
	Sum of sex lowest tertiles		Sum of sex middle tertiles			Sum of sex highest tertiles
	n = 1249		n = 1252			n = 1240			Trend test
			HR	95% CI	P-value	HR	95% CI	P value	P value
CVD	37			28			27
Sex and age adjusted model	1.00	(Ref)	0.88	(0.54–1.44)	0.605	0.72	(0.44–1.19)	0.201	0.202
Multivariable adjusted model	1.00	(Ref)	0.91	(0.52–1.58)	0.730	0.40	(0.20–0.82)	0.012	0.015
Stroke	30			22			21
Sex and age adjusted model	1.00	(Ref)	0.85	(0.49–1.48)	0.568	0.70	(0.40–1.23)	0.215	0.214
Multivariable adjusted model	1.00	(Ref)	0.89	(0.48–1.65)	0.721	0.29	(0.13–0.68)	0.005	0.006

Sex and age adjusted model: Adjusted for sex and age
Multivariable adjusted model: sex and age adjusted model + adjusted for smoking (currently, past, never), drinking (currently, past, never, job (y/n), BMI, hypertension (y/n), dyslipidemia(y/n), diabetes (y/n), and physical activity other than during leisure time (sleep, job, transportation, other)
CVD cardiovascular disease; BMI body mass index; MET metabolic equivalent; HR hazard ratio; CI confidence interval

ISSN: 1471-2261