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Table 1 Baseline characteristics

From: Impact of renin–angiotensin–aldosterone system inhibition on mortality in critically ill COVID-19 patients with pre-existing hypertension: a prospective cohort study

Characteristic

ACEi/ARB

Available number

Non-ACEi/ARB

Available number

Demographics

Age (years), median (IQR)

65 (57–73)

538

66 (55–73)

199

Male, n (%)

358 (67)

538

123 (62)

199

BMI (kg/m2), median (IQR)

29.4 (26.2–34.0)

489

29.3 (24.9–34.0)

190

Ethnicity, n (%)

 Aboriginal

7 (1)

501

1 (1)

191

 Arab

11 (2)

501

4 (2)

191

 Black

58 (12)

501

48 (25)

191

 East Asian

20 (4)

501

10 (5)

191

 South Asian

21 (4)

501

13 (7)

191

 West Asian

3 (1)

501

1 (1)

191

 Latin American

102 (20)

501

17 (9)

191

 Other

26 (5)

501

14 (7)

191

 White

253 (50)

501

83 (43)

191

Geographic region, n (%)

 Africa

19 (4)

538

0 (0)

199

 Asia

53 (10)

538

37 (19)

199

 Australia

6 (1)

538

1 (1)

199

 Europe

164 (30)

538

57 (29)

199

 Latin America and the Caribbean

102 (19)

538

8 (4)

199

 Northern America

194 (36)

538

96 (48)

199

Admission signs and symptoms

Heart rate (beats/minute), median (IQR)

92 (80–105)

510

92 (79–106)

182

Systolic BP (mmHg), median (IQR)

130 (114–148)

508

127 (110–150)

184

Diastolic BP (mmHg), median (IQR)

72 (62–82)

508

70 (61–83)

184

Respiratory rate (breaths/minute), median (IQR)

25 (20–30)

485

24 (20–30)

177

Oxygen saturation (%), median (IQR)

91 (84–95)

511

94 (89–97)

187

Cough, n (%)

377 (75)

502

127 (70)

181

Fever, n (%)

408 (79)

514

140 (75)

186

Malaise, n (%)

275 (58)

478

77 (44)

175

Dyspnoea, n (%)

433 (82)

526

156 (82)

190

Reported comorbidities

Smoking, n (%)

166 (40)

412

67 (44)

151

Diabetes, n (%)

250 (47)

534

88 (45)

197

Chronic cardiac disease, n (%)

133 (25)

534

59 (30)

198

Chronic pulmonary disease, n (%)

72 (13)

536

41 (21)

197

Chronic kidney disease, n (%)

80 (15)

535

51 (26)

197

Chronic neurological disorder, n (%)

34 (6)

534

17 (9)

197

Severe liver disease, n (%)

27 (5)

536

21 (11)

198

Malignant neoplasm, n (%)

32 (6)

535

13 (7)

197

Reported use of anti-hypertensive drugs on admission

Diuretic, n (%)

92 (20)

458

46 (23)

199

Calcium channel blocker, n (%)

113 (25)

458

112 (56)

199

β-blocker, n (%)

111 (24)

458

110 (55)

199

α-blocker, n (%)

6 (1)

458

4 (2)

199

  1. ACEi angiotensin-converting enzyme inhibitor, ARB angiotensin II receptor blocker, BMI body mass index