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Table 2 Key information of the included studies

From: Efficacy and safety of a bridging strategy that uses intravenous platelet glycoprotein receptor inhibitors for patients undergoing surgery after coronary stent implantation: a meta-analysis

Reference

No. of patients

MACE definition

The follow-up time

DAPT (No. of patients)

Dose for bridging therapy

Xia (2013)

21

Cardiovascular death, MI, target lesion revascularization

3 months

Aspirin(21)

Clopidogrel(21)

0.1 µg/kg/min

0.05 µg/kg/min(if CrCl < 30 mL/min)

Walker (2017)

20

Death,repeat myocardial infarction, stent thrombosis,or target lesion revascularization

During hospitalization

Aspirin(20)

Clopidogrel(16)

Ticagrelor(4)

0.1 µg/kg/min

0.05 µg/kg/min(if CrCl < 30 mL/min)

Savonitto (2010)

30

Cardiovascular death, MI, an acute occlusion of the target lesion

During hospitalization

Aspirin(30)

Clopidogrel(30)

0.1 µg/kg/min

0.05 µg/kg/min(if CrCl < 30 mL/min)

Polito (2018)

21

Death, reinfarction, cardiovascular events

21.6 months

Aspirin(21)

Clopidogrel(1)

Ticagrelor(13)

Prasugrel(7)

0.1 µg/kg/min

0.05 µg/kg/min(if CrCl < 30 mL/min)

Marcos (2011)

36

Death, repeat myocardial infarction, target vessel revascularisation, target lesion revascularization, stent thrombosis

30 days

Aspirin(36)

Clopidogrel(36)

Not mentioned

Servi (2016)

87

All-cause death; myocardial infarction; definite stent thrombosis

30 days

Aspirin(87)

Clopidogrel(84)

Ticagrelor(1)

ticlopidine (2)

0.1 µg/kg/min

0.05 µg/kg/min(if CrCl < 30 mL/min)

Waldron (2017)

30

Myocardial infarction or death

30 days

Aspirin(30)

Clopidogrel(30)

2 µg/kg/min

1 µg/kg/min(if CrCl < 30 mL/min)

Rassi (2012)

100

Death, myocardial infarction, urgent revascularization, and ischemic stroke

During hospitalization

Aspirin

Clopidogrel prasugrel (No specific number)

Not mentioned

Morrison (2012)

19

Stent thrombosis acute coronary syndrome, and death

30 days

Aspirin(19)

Clopidogrel(19)

2 µg/kg/min

1 µg/kg/min(if CrCl < 30 mL/min)

Barra (2016)

18

Stent thrombosisand death

90 days

Aspirin(18)

Clopidogrel(15)

Prasugrel(3)

2 µg/kg/min

1 µg/kg/min(if CrCl < 30 mL/min)