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Table 1 Key characteristics and findings of the included studies

From: Efficacy and safety of a bridging strategy that uses intravenous platelet glycoprotein receptor inhibitors for patients undergoing surgery after coronary stent implantation: a meta-analysis

References

Country

No. of patients

Age

Type

Non-cardiac surgery(n)

Type of stents

Time from PCI to surgery (months)

Bridging protocol

Non-MACE

Non-reoperation

Number

Success rate(95% CI)

Number

Success rate(95% CI)

Xia (2013)

China

21

63

Obs,Prosp

21(100%)

DES

6

Initiated tirofiban 4.8 days prior

to surgery; stopped tirofiban

4 h prior to surgery

21

100% (83.9–100%)

21

100% (83.9–100%)

Walker (2017)

USA

20

72

Obs,Restrosp

11(55%)

DES

1.1

Initiated tirofiban 3.5 days prior

to surgery; stopped tirofiban

5.4 h prior to surgery

18

90.0% (68.3–98.8%)

20

100% (83.2–100%)

Savonitto (2010)

USA

30

65

Obs,Prosp

21(70%)

DES

4

Initiated tirofiban 4 days prior

to surgery; stopped tirofiban

5 h prior to surgery

30

100% (88.4–100%)

30

100% (88.4–100%)

Polito (2018)

Italy

21

62

Obs,Restrosp

0(0%)

DES

0,23

Initiated tirofiban 3 days prior

to surgery; stopped tirofiban

4 h prior to surgery

20

95.2% (76.2–99.9%)

21

100% (83.9–100%)

Marcos (2011)

Netherlands

36

66

Obs,Restrosp

21(58%)

Mixed(58%DES)

2.6

Initiated tirofiban 4 days prior

to surgery; stopped tirofiban

4 h prior to surgery

36

100% (90.3–100%)

35

97.2% (85.5–99.9%)

Servi (2016)

Italy

87

67.4

Obs,Restrosp

59(68%)

91%

3.4

Initiated tirofiban 3 days prior

to surgery; stopped tirofiban

4 h prior to surgery

85

97.7% (91.9–99.7%)

87

100% (95.8–100%)

Waldron (2017)

USA

30

65

Obs,Restrosp

30(100%)

DES

Not mention

Used eptifibatide, not mention bridging details

27

90.0% (73.5–97.9%)

30

100% (88.4–100%)

Rassi (2012)

USA

100

63.2

Obs,Restrosp

29(29%)

Mixed(89%DES)

5.8

Initiated eptifibatide 5.3 days prior

to surgery; stopped eptifibatide

7 h prior to surgery

93

93.0% (86.1–97.1%)

90

90.0% (82.4–95.1%)

Morrison (2012)

USA

19

65

Obs,Restrosp

6(32%)

DES

3.5

Initiated eptifibatide 2.6 days prior

to surgery; stopped eptifibatide 10 h prior to surgery

19

100% (82.4–100%)

18

94.7% (74.0–99.9%)

Barra (2016)

USA

18

61.9

Obs,Restrosp

13(72%)

Mixed(89%DES)

3.5

Initiated eptifibatide 2.7 days prior

to surgery; stopped eptifibatide 6 h prior to surgery

18

100% (81.5–100%)

17

94.4% (72.7–99.9%)