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Table 3 Association of significant SNPs with the phenotypic categories of coronary artery disease

From: Analysis of 61 SNPs from the CAD specific genomic loci reveals unique set of SNPs as significant markers in the Southern Indian population of Hyderabad

SNP (minor/major allele) MAF in controls N = 480 Angina(n = 73) Acute coronary syndrome (n = 159) Myocardial infarction (n = 75)
MAF OR (95%CI) p value MAF OR (95%CI) p value MAF OR (95%CI) p value
rs10455872 (G/A) 0.007 0.218 37.6 (16.2–87.4) *1.80e−37 0.240 42.5 (19.3–93.7) *3.06e−47 0.068 9.90 (3.71–26.5) *2.63e−08
rs782590 (T/C) 0.222 0.340 1.81 (1.24–2.64) *0.002 0.290 1.43 (1.07–1.91) 0.014 0.311 1.58 (1.08–2.31) 0.017
rs6725887 (C/T) 0.020 0.185 11.1 (5.98–20.6) *2.44e−20 0.172 10.2 (5.91–17.4) *1.60e−23    
rs173539 (T/C) 0.011     0.033 3.09 (1.15–8.33) 0.019 0.092 9.26 (3.26–26.3) *5.28e−07
rs174546 (T/C) 0.095 0.151 1.68 (1.02–2.77) 0.041       
rs7767084 (C/T) 0.307 0.226 0.66 (0.44–0.99) 0.046       
rs1122608 (T/G) 0.239     0.297 1.34 (1.01–1.79) 0.040    
rs4846922 (T/C) 0.379        0.542 1.93 (1.36–2.75) *0.0002
  1. Bold indicates significant p value (of the odds ratio)
  2. *p value significant after correction for multiple testing