Analysis of 61 SNPs from the CAD specific genomic loci reveals unique set of SNPs as significant markers in the Southern Indian population of Hyderabad

Table 3 Association of significant SNPs with the phenotypic categories of coronary artery disease

SNP (minor/major allele)	MAF in controls N = 480	Angina(n = 73)			Acute coronary syndrome (n = 159)			Myocardial infarction (n = 75)
SNP (minor/major allele)	MAF in controls N = 480	MAF	OR (95%CI)	p value	MAF	OR (95%CI)	p value	MAF	OR (95%CI)	p value
rs10455872 (G/A)	0.007	0.218	37.6 (16.2–87.4)	*1.80e⁻³⁷	0.240	42.5 (19.3–93.7)	*3.06e⁻⁴⁷	0.068	9.90 (3.71–26.5)	*2.63e⁻⁰⁸
rs782590 (T/C)	0.222	0.340	1.81 (1.24–2.64)	*0.002	0.290	1.43 (1.07–1.91)	0.014	0.311	1.58 (1.08–2.31)	0.017
rs6725887 (C/T)	0.020	0.185	11.1 (5.98–20.6)	*2.44e⁻²⁰	0.172	10.2 (5.91–17.4)	*1.60e⁻²³
rs173539 (T/C)	0.011				0.033	3.09 (1.15–8.33)	0.019	0.092	9.26 (3.26–26.3)	*5.28e⁻⁰⁷
rs174546 (T/C)	0.095	0.151	1.68 (1.02–2.77)	0.041
rs7767084 (C/T)	0.307	0.226	0.66 (0.44–0.99)	0.046
rs1122608 (T/G)	0.239				0.297	1.34 (1.01–1.79)	0.040
rs4846922 (T/C)	0.379							0.542	1.93 (1.36–2.75)	*0.0002

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