Table 2 Longitudinal distribution of atherosclerotic plaque in RA
Variables | All | Segments | Pa | ||
|---|---|---|---|---|---|
Proximal 0–50 mm | Middle 50–100 mm | Distal 100–150 mm | |||
Patient-level | |||||
Plaque present | 76 (31.8) | 47 (19.7)b | 28 (11.7) | 50 (20.9)c | 0.016 |
 Fibrous | 50 (20.9) | 28 (11.7) | 18 (7.5) | 24 (10.0) | 0.300 |
 Lipid | 39 (16.3) | 20 (8.4)b | 6 (2.5) | 21 (8.8)c | 0.008 |
 Calcified | 15 (6.3) | 5 (2.1) | 6 (2.5) | 14 (5.9)d | 0.049 |
Total lesion length, mm | 7.1 (3.2–13.1) | 4.9 (2.5–9.5) | 5.4 (2.1–9.9) | 6.0 (3.1–13.5) | 0.394 |
Microvessel present | 60 (25.1) | 16 (6.7) | 30 (12.6)b | 49 (20.5)c,d | < 0.001 |
Macrophage present | 29 (12.1) | 7 (2.9) | 10 (4.2) | 19 (7.9)d | 0.033 |
Plaque-level | |||||
Number of Plaques | 148 | 55 (37.2) | 30 (20.3) | 63 (42.6) | Â |
Plaque phenotype | |||||
 Fibrous | 72 (48.6) | 29 (40.3) | 18 (25.0) | 25 (34.7) |  |
 Lipid | 50 (33.8) | 21 (42.0) | 6 (12.0) | 23 (46.0) |  |
 Calcified | 26 (17.6) | 5 (19.2) | 6 (23.1) | 15 (57.7) |  |
Quantitative analysis | |||||
 Plaque (mm) | 4.9 (2.3–8.3) | 3.6 (2.1–7.8) | 5.5 (2.1–7.8) | 4.8 (3.0–8.4) | 0.389 |
 Fibrous (mm) | 3.4 (1.6–7.7) | 3.3 (1.3–8.1) | 5.0 (1.7–7.4) | 3.1 (1.6–8.7) | 0.841 |
 Calcified (mm) | 8.1 (4.6–20.8) | 10.3 (2.0–19.1) | 14.2 (4.3–29.5) | 7.8 (4.7–16.3) | 0.806 |
 Maximal depth (mm) | 0.21 (0.16–0.33) | 0.16 (0.12–0.22) | 0.17 (0.14–0.23) | 0.27 (0.18–0.56) | 0.049 |
 Maximum arc (°) | 62.8 (43.2–101.7) | 55.9 (19.3–82.3) | 70.2 (44.9–119.6) | 66.2 (43.8–101.0) | 0.470 |
 FCT (μm) | 120 (40–170) | 60 (40–170) | 90 (30–120) | 130 (40–250) | 0.389 |
 Lipid (mm) | 4.9 (3.1–6.9) | 4.9 (2.6–6.7) | 5.4 (2.5–9.0) | 4.8 (3.3–7.0) | 0.812 |
 FCT (μm) | 220 (140–330) | 180 (120–280) | 420 (210–640) | 250 (140–340) | 0.091 |
 Maximum arc (°) | 89.6 (78.3–127.3) | 87.3 (80.5–121.1) | 119.6 (102.7–127.9) | 88.4 (70.0–128.0) | 0.462 |