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Table 2 Demographic and medical characteristics of the sample

From: The use of serotonin reuptake inhibitors increases the risk of bleeding in patients with assist devices

 

Global

Patients

p value

With bleedings

Without bleeding

n = 92

n = 71

n = 21

Age at time of implantation (median)

55.03

55.19

52.21

.199a

In years (range)

19.68–72.31

23.75–72.31

19.68–66.44

 

Gender

   

.755c

Male

82.8%

83.1%

81.0%

 

Female

17.4%

16.9%

19.0%

 

Hypercholesterolemia

43.5%

40.8%

52.4%

.493b

Arterial hypertension

30.4%

25.4%

47.6%

.093b

Chronic renal failure

52.2%

57.7%

43.3%

.086b

Diabetes mellitus type II

25.0%

26.8%

19.0%

.575c

Nicotine

   

.277b

Current

23.9%

20.9%

33.3%

 

Past

38.6%

37.3%

42.9%

 

Never

37.5%

41.8%

23.8%

 

VAD Model

   

.886b

Continuous-flow

    

(HeartWare, Berlin Heart Incor)

60.9%

62.0%

57.1%

 

Pulsatile-flow (Berlin Heart Excor)

39.1%

38.0%

42.9%

 

Type of cardiomyopathy

   

.947b

Ischemic Cardiomyopathy

37.0%

38.0%

33.3%

 

dilated Cardiomyopathy

35.9%

35.2%

38.1%

 

Other etiologies

 < 10% each

-

-

–

Platelet aggregation inhibitors

   

.689c

Dual

25.0%

22.5%

33.3%

 

Mono

69.6%

71.8%

61.9%

 

None

5.4%

5.7%

4.8%

 

Anticoagulants

98.9%

100%

95.2%

–

NSAID (other than acetylsalicylic acid)

4.3%

5.6%

0.0%

–

  1. Statistical analyses: a Mann–Whitney U-test, b Pearson’s Chi squared test, comparing patients with and without bleedings for each variable (in bold), c Fisher’s exact test. NSAID = non-steroidal anti-inflammatory drug. VAD = ventricular assist device