Cardiac disease and prognosis associated with ventricular tachyarrhythmias in young adults and adults

Table 4 Multivariate Cox regression models

Variables	All-cause mortality at 2.5 years
	Young adults 20–34 years old 20–34 years old (n = 92; 36%)			Adults 35–45 years old 35–45 years old (n = 167; 64%)
	HR	95% CI	p value	HR	95% CI	p value
Males	0.095	0.007–1.240	0.273	1.135	0.299–4.310	0.852
Chronic kidney disease	1.064	0.090–1.064	0.961	2.492	0.822–7.553	0.106
LVEF < 35%	33.590	2.395–471.404	0.009	2.296	0.822–7.553	0.164
AMI	2.073	0.149–28.910	0.588	1.053	0.364–3.047	0.924
Atrial fibrillation	11.090	0.618–199.219	0.102	1.469	0.364–3.047	0.459
Ventricular fibrillation	3.840	0.322–44.354	0.281	2.975	0.904–9.796	0.073

Variables	Composite endpoint at 2.5 years (cardiac death at 24 h, recurrent ventricular tachyarrhythmias, appropriate ICD therapies)
	Young adults 20–34 years old			Adults 35–45 years old
	HR	95% CI	p value	HR	95% CI	p value
Males	0.526	0.179–1.543	0.242	0.763	0.278–2.095	0.599
Chronic kidney disease	1.349	0.368–5.025	0.645	1.532	0.539–4.351	0.423
LVEF < 35%	0.894	0.114–7.013	0.915	1.739	0.594–5.096	0.313
AMI	0.830	0.084–8.198	0.873	0.741	0.234–2.349	0.611
Atrial fibrillation	1.354	0.165–11.127	0.778	0.995	0.348–2.848	0.922
Ventricular fibrillation	0.443	0.105–1.875	0.296	0.765	0.293–1.999	0.584

Bold type indicates statistical significance p < 0.05
AMI, acute myocardial infarction; CI, confidence interval; HR, Hazard ratio; LVEF, left ventricular ejection fraction

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