Table 2 Cardiac comorbidities at index hospitalization
Characteristic | Young adults 20–34 years old (n = 92; 36%) | Adults 35–45 years old (n = 167; 64%) | p value |
|---|---|---|---|
Left ventricular function, n (%) | |||
LVEF > 55% | 33 (36) | 57 (34) | 0.188 |
LVEF 45–55% | 14 (15) | 17 (10) | |
LVEF 35–44% | 11 (12) | 22 (13) | |
LVEF < 35% | 5 (5) | 22 (13) | |
Not documented | 29 (32) | 49 (29) | 0.714 |
Primary cardiomyopathies, n (%) | 11 (12) | 16 (10) | |
Dilated cardiomyopathy | 5 (5) | 11 (7) | 0.712 |
Hypertrophic cardiomyopathy | 0 (0) | 5 (3) | 0.200 |
Arrhythmogenic right ventricular dysplasia | 6 (7) | 0 (0) | 0.001 |
Noncompaction cardiomyopathy | 0 (0) | 0 (0) | – |
Restrictive cardiomyopathy | 0 (0) | 0 (0) | – |
Channelopathies, n (%) | 17 (18) | 19 (12) | |
Brugada syndrome | 13 (14) | 16 (10) | 0.245 |
Short QT syndrome | 0 (0) | 0 (0) | – |
Long QT syndrome | 4 (4) | 3 (2) | 0.168 |
Other causes, n (%) | |||
Myocarditis | 7 (8) | 4 (2) | 0.027 |
Takotsubo cardiomyopathy | 0 (0) | 0 (0) | – |
High degree AV-block | 1 (1) | 1 (1) | 0.668 |
Intoxication | 6 (7) | 4 (2) | 0.064 |
Hyperkalemia | 4 (4) | 17 (10) | 0.099 |
Hypokalemia | 18 (20) | 17 (10) | 0.034 |
Coronary artery disease, n (%) | |||
Prior CAD | 4 (4) | 20 (12) | 0.043 |
Prior AMI | 1 (1) | 16 (10) | 0.008 |
AMI at index | 10 (11) | 46 (28) | 0.001 |
STEMI | 4 (4) | 20 (12) | 0.018 |
NSTEMI | 6 (7) | 26 (16) | 0.034 |
Coronary angiography at index | 26 (28) | 96 (58) | 0.001 |
No evidence of CAD | 16 (62) | 45 (47) | 0.089 |
Evidence of CAD | 10 (38) | 51 (53) | 0.184 |
1-vessel | 10 (100) | 31 (61) | 0.003 |
2-vessel | 0 (0) | 15 (29) | |
3-vessel | 0 (0) | 5 (10) | |
Intracoronary thrombus | 5 (19) | 13 (13) | 0.455 |
CABG | 0 (0) | 2 (2) | 0.458 |
CTO | 0 (0) | 9 (9) | 0.105 |
PCI | 10 (100) | 43 (84) | 0.564 |
RCA | 5 (50) | 14 (30) | 0.384 |
LMT | 0 (0) | 0 (0) | – |
LAD | 5 (50) | 23 (50) | 1.000 |
RIM | 0 (0) | 0 (0) | – |
RCX | 0 (0) | 9 (20) | 0.023 |
Sent to CABG | 0 (0) | 0 (0) | – |
Electrophysiological examination, n (%) | 45 (49) | 68 (41) | 0.203 |
VT ablation | 14 (31) | 18 (26) | 0.175 |
Presence of ICD at discharge, n (%) | 35 (38) | 63 (38) | 0.959 |
Type of ICD, n (%) | |||
ICD | 31 (89) | 58 (92) | 0.788 |
CRT-D | 0 (0) | 1 (2) | |
s-ICD | 4 (11) | 4 (6) | |
ICD programming, BPM, median (IQR) | |||
VT detection threshold | 191 (176–205) | 171 (167–176) | 0.735 |
VF detection threshold | 231 (231–240) | 176 (167–176) | 0.014 |