Fig. 1
Fasting serum lipid levels. A Cholesterol and triglyceride levels for controls (white circles), ApoBR3500Q heterozygotes (gray squares), and ApoBR3500Q homozygotes (black triangles). B Several ApoBR3500Q heterozygotes (gray bars) had LDL-C in the normal range (< 130 mg/dL) or below the threshold for suspecting heterozygous FH (160 mg/dL with a family history or 190 mg/dL). All ApoBR3500Q homozygotes (black bar) had LDL-C below 500 mg/dL, the level typically associated with homozygous FH. C LDL-C among controls, ApoBR3500Q heterozygotes, and ApoBR3500Q homozygotes (black triangles) compared to subject age. ApoBR3500Q homozygotes (black triangles) were not included in statistical analysis due to small sample size but are presented for completeness. LDL-C did not correlate significantly with age in controls or ApoBR3500Q heterozygotes. LDL-C association with age measured by Spearman’s rho (rs)