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Table 2 Baseline characteristics of the patients included

From: Safety and efficacy of anti-inflammatory therapy in patients with coronary artery disease: a systematic review and meta-analysis

 

Mehdi Akrami et al. [7]

LoDoCO2 [9]

CIRT [22]

COLCOT [8]

CANTOS [11]

STABILITY [15]

SOLID-TIMI [16]

VISTA-16 [14]

COPS [20]

FRANCIS [21]

Patients (n)

120/129

2762/2760

2391/2395

2366/2379

3344/6717

7924/7904

6504/6522

2572/2573

396/399

313/311

Age (mean)

56.9/56.9

65.8/65.9

65.6 /66.0

60.6/60.5

61.1/61.1

65.0/65.0

64.0/64.0

61.0/60.7

59.7/60.0

58.5/59.6

Male (%)

86.0/87.0

83.5/85.9

80.7/81.8

80.1/81.6

74.1/74.4

81.5/81.0

74.6/74.5

73.1/74.4

81.3/77.7

73.5/75.9

Smokers (%)

52.0/49.0

11.5/12.0

11.2/11.3

29.9/29.8

22.9/43.1

19.8/21.0

18.9/19.1

33.2/33.4

32.3/37.3

23.3/21.9

Hypertension (%)

52.0/59.0

51.4/50.3

90.0 /90.6

50.1/52.0

79.1/79.9

73.7/73.0

74.3/76.8

50.8/49.9

86.6/88.1

Diabetes (%)

27.0/32.0

17.8/18.7

33.0/34.4

19.5/20.9

39.9/40.1

33.6/34.0

35.0/34.1

31.1/31.2

18.9/19.8

26.8/28.0

Previous ACS (%)

84.1/84.6

60.7/60.9

15.6/16.7

87.9/88.2

59.1/69.1

31.0/31.2

29.6/30.2

59.0/59.0

Previous PCI (%)

16.0/20.0

76.0/75.3

58.4/59.3

16.6/17.0

65.6/67.3

50.3/50.3

23.6/24.2

18.6/17.7

51.0/50.0

Previous CABG (%)

4.0/3.0

11.5/14.2

42.2/43.1

2.9/3.4

14.0/14.0

33.4/32.8

7.1/6.3

15.0/19.0

Medication use — no. (%)

Antiplatelet

100.0/100.0

90.0/80.6

87.1/85.8

98.6/98.9

91.1/92.1

100.0/100.0

96.4/96.5

91.3/91.8

99.0/98.0

92.7/91.0

ACEI or ARB

100.0/100.0

72.2/71.2

72.6/72.0

/

79.6/79.8

82.7/82.4

82.5/82.3

88.0/86.0

85.9/81.7

Beta-blocker

100.0/100.0

61.3/62.9

78.2/79.5

89.4/88.3

87.2/87.4

83.9/82.9

81.0/85.0

84.0/84.6

Statins

100.0/100.0

93.9/94.0

86.1/85.7

98.9/99.1

91.1/91.1

100.0/100.0

94.3/94.9

98.7/99.0

98.0/99.0

Median lipid levels (IQR) — mg/dl

LDL cholesterol

68.0/68.0

82.8/82.0

74.9/74.9

105.1/105.0

61.0/60.3

HDL cholesterol

41.0/41.0

44.5/43.7

44.4/44.8

43.2/43.3

  1. ACS, acute coronary syndrome; PCI, percutaneous coronary intervention; CABG, coronary artery bypass grafting; ACEI, angiotensin-converting enzyme inhibitors; ARB, angiotensin receptor blockers; IQR, inter quartile range