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Fig. 2 | BMC Cardiovascular Disorders

Fig. 2

From: Major vault protein attenuates cardiomyocyte injury in doxorubicin-induced cardiomyopathy through activating AKT

Fig. 2

Expression of MVP is up-regulated in DOX-treated heart tissues and cardiomyocytes. A The morphology of the hearts of the two groups. B Representative immunohistochemistry images of MVP in murine hearts. C Western blot and a quantitative result of MVP in DOX-treated hearts. D Western blot and a quantitative result of MVP in H9C2 cardiomyocytes (three independent experiment). E, F The mRNA levels of MVP/p53/Ppargc1a/Ppargc1b in DOX-treated hearts. N = 6, values represent the mean ± SEM. *P < 0.05, **P < 0.01, ***P < 0.001

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