The best QT correction formula in a non-hospitalized population: the Fasa PERSIAN cohort study

Table 2 Baseline characteristics of subjects according to gender

Variables	Male n = 3078	Female n = 3993	p value
Age (years)	48.49 ± 9.28	48.69 ± 9.40	0.367^a
Heart rate (bpm)	65.99 ± 10.87	75.16 ± 11.59	< 0.001^a
QRS duration (ms)	98.50 ± 10.70	95.46 ± 9.90	< 0.001^a
QT interval (ms)	403.82 ± 36.32	395.63 ± 37.19	< 0.001^a
QTcB (ms)	420.24 ± 31.91	439.63 ± 33.58	< 0.001^a
QTcFri (ms)	414.40 ± 29.57	424.05 ± 32.63	< 0.001^a
QTcFra (ms)	414.09 ± 29.14	423.83 ± 30.36	< 0.001^a
QTcH (ms)	414.30 ± 29.33	422.16 ± 29.92	< 0.001^a
QTcR (ms)	422.16 ± 29.75	429.40 ± 31.05	< 0.001^a
QTcD (ms)	417.14 ± 30.18	431.46 ± 32.15	< 0.001^a
All-cause mortality	46 (1.5)	33 (0.8)	0.008^b
Cardiac mortality	26 (0.8)	19 (0.5)	0.053^b
Survival days⁺	1154.27 ± 115.23	1172.65 ± 107.32	< 0.001^a
Subjects with mortality	600.08 ± 312.08	655.51 ± 346.86	< 0.001^a
Subjects without mortality	1162.68 ± 85.45	1176.96 ± 91.61	< 0.001^a
Selected medications†	691 (22.4)	1124 (28.1)	< 0.001^b
CVD history	302 (9.8)	557 (13.9)	< 0.001^b
Stroke	40 (1.3)	52 (1.3)	0.992^b
CHD	274 (8.9)	522 (13.1)	< 0.001^b
MI	77 (2.5)	52 (1.3)	< 0.001^b
Medical conditions	617 (20.0)	1773 (44.4)	< 0.001^b
Diabetes	251 (8.2)	638 (16.0)	< 0.001^b
Hypertension	354 (11.5)	1083 (27.1)	< 0.001 ^b
Renal failure	35 (1.1)	33 (0.8)	0.184^b
Chronic lung disease	50 (1.6)	85 (2.1)	0.124^b
Hepatitis	3 (0.1)	0 (0.0)	0.048^b
Thyroid dysfunction	76 (2.5)	563 (14.1)	< 0.001^b

Data are reported as mean ± standard deviation or as count (percentages). p value reported as the result of ^aIndependent sample t and ^bChi-square tests. Statistically significant p values are bolded (p value < 0.05)
bpm beats per minute, QTc corrected QT interval, Bazett’s correction formula (QTcB), Fridericia’s correction formula (QTcFri), Dmitrienko’s correction formula (QTcD), Framingham’s correction formula (QTcFra), Hodges’s correction formula (QTcH), Rautaharju’s correction formula (QTcR), ms milliseconds
⁺Survival days calculated from the day of electrocardiogram recording until their last follow-up in Fasa PERSIAN cohort Study
^†Selected medications is a list of drugs with known and possible risks for Torsade de Pointes, which accounted for 187 cardiac and non-cardiac drugs in total [35]

ISSN: 1471-2261