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Fig. 3 | BMC Cardiovascular Disorders

Fig. 3

From: Recombinant human endostatin combined with radiotherapy promotes cardiomyocyte apoptosis in rats via TGFβ1/Smads/CTGF signaling pathway

Fig. 3

Structural changes of rat cardiomyocytes after different treatments as observed under TEM (n=5). Normal structure of nucleusand some autophagosomes in the cytoplasm just as in normal cardiomyocytes; aberration of nucleus after radiation indicated by red arrow in the leftpane; mitochondrial apoptosisseen in the cell as shown by the red circle and arrow in the middle and right panes; ES treatment resulted in chromatin shrinkage and condensed as black starry spots in nucleus indicated by red arrow in the left pane; mitochondrial apoptosis and some autophagosomes (indicated by red arrow in right pane) seen in the cell; radiation + ES combination treatment resulted in large mass of chromatin clot in the nucleus, serious structural damage of intracellular organelles, and many vacuole structures

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BMC Cardiovascular Disorders

ISSN: 1471-2261

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