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Table 4 Interaction analysis of the effects of HLP plus HTN on risk of ischemic stroke

From: Hyperlipidemia and hypertension have synergistic interaction on ischemic stroke: insights from a general population survey in China

Model

Effect value

95% CI

Unadjusted model

  

 Additive scale

  

  RERI

2.23

(1.278–3.182)

  AP

0.378

(0.248–0.507)

  S index

1.833

(1.376–2.442)

 Multiplicative scale

  

  OR

3.177

(2.711–3.724)

Model 1

  

 Additive scale

  

  RERI

1.504

(0.836–2.172)

  AP

0.378

(0.231–0.526)

  S index

2.023

(1.337–3.061)

 Multiplicative scale

  

  OR

2.536

(2.156–2.984)

Model 2

  

 Additive scale

  

  RERI

1.053

(0.458–1.648)

  AP

0.313

(0.146–0.479)

  S index

1.8

(1.157–2.801)

 Multiplicative scale

  

 OR

2.163

(1.817–2.575)

  1. Model 1: adjusted for age and sex
  2. Model 2: adjusted for age, sex, race, education level, family income, current smoking and drinking status, physical activity, BMI, diabetes, family history of stroke, and atrial fibrillation
  3. AP, attributable proportion due to interaction; BMI, body mass index; CI, confidence interval; HLP, hyperlipidemia; HTN, hypertension; OR, odds ratio; RERI, relative excess risk due to interaction; S index, synergy index
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BMC Cardiovascular Disorders

ISSN: 1471-2261

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