Fig. 4

Effect of miR-138-5p targeting RUNX2 on Wnt/β-catenin signaling pathway. A Western blot-based detection of Wnt5a and β-catenin protein expression in osteogenically differentiated hAVICs transfected with miR-138-5p mimics or inhibitor. **P < 0.01 versus Normal group; ^##P < 0.01 versus Calcified group; &P < 0.05 versus Calcified-NC group. B Western blot-based detection of Wnt5a and β-catenin protein expression in osteogenically differentiated hAVICs transfected with miR-138–5 mimics or miR-138-5p mimics combined with RUNX2 overexpression plasmid