Fig. 5

Effect of B1 and Tr cells on the plasma levels of IL-10 and TNF-α. The plasma IL-10 and TNF-α levels were assayed by ELISA in the three groups. A The levels of plasma IL-10 and TNF-α were analyzed among DCM, HF and HC groups, and between patients with DCM who were β1-AR autoantibody-positive and h β1-AR autoantibody-negative. No significant difference was found in the levels of plasma IL-10 and TNF-α among the three groups, and between the two DCM subgroups. Bars represent the means ± standard deviation. Data were compared using one-way ANOVA or independent sample t test. B, C The correlation between the percentage of B1 cells and the levels of plasma IL-10 and TNF-α in the DCM group. There was no significant correlation between the proportion of B1 cells and the levels of plasma IL-10 (B) and TNF-α (C) in the DCM group. D–E The correlation between the percentage of peripheral Tr cells and the levels of plasma IL-10 and TNF-α in the DCM group. No significant correlation was observed between the proportion of Tr cells and levels of IL-10 (D) and TNF-α (E). Each point represents an individual in figure B-E. Pearson’s correlation analysis was performed