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Fig. 4 | BMC Cardiovascular Disorders

Fig. 4

From: SERPINB1 overexpression protects myocardial damage induced by acute myocardial infarction through AMPK/mTOR pathway

Fig. 4

Overexpression of SERPINB1 reduced apoptosis of myocardial cells induced by oxygen–glucose deprivation (OGD) treatment. A The expression of SERPINB1 of myocardial cells H9C2 after OGD treatment for 0, 6, 12 or 24 h was measured by western blot. *P < 0.5 vs. 0 h. B The expression of SERPINB1 of myocardial cells H9C2 after pcDNA3.1 SERPINB1 transfection was measured by western blot. C The cell viability of myocardial cells H9C2 after pcDNA3.1 SERPINB1 transfection was measured by CCK-8 assay. D, E The cell apoptosis of myocardial cells H9C2 after pcDNA3.1 SERPINB1 transfection was measured by flow cytometry. F The protein of Bax, Bcl-2, and caspase-3 of myocardial cells H9C2 after pcDNA3.1 SERPINB1 transfection was measured by western blot. *P < 0.05 vs. Control group. #P < 0.05 vs. OGD + pc-NC group

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BMC Cardiovascular Disorders

ISSN: 1471-2261

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