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Table 4 Predictors of MACE

From: Clinical values of resting electrocardiography in patients with known or suspected chronic coronary artery disease: a stress perfusion cardiac MRI study

 

Univariable analysis

Multivariable analysis

HR (95%CI)

P value

HR (95%CI)

P value

Age

1.02 (0.99, 1.04)

0.13

1.01 (0.99, 1.03)

0.23

Men

1.06 (0.54, 2.05)

0.87

0.94 (0.60, 1.49)

0.8

Body mass index

0.95 (0.91, 1.001)

0.05

  

Systolic blood pressure

0.99 (0.98, 1.01)

0.88

  

Diastolic blood pressure

0.97 (0.96, 0.99)

0.003

0.98 (0.96, 1.00)

0.05

Heart rate

0.99 (0.98, 1.01)

0.92

  

Hypertension

0.79 (0.28, 2.23)

0.65

  

Hyperlipidemia

0.93 (0.39, 2.24)

0.87

  

Diabetes mellitus

1.43 (0.73, 2.83)

0.3

1.77 (1.14, 2.76)

0.01

Cigarette smoking

1.05 (0.46, 2.40)

0.91

  

History of CAD

3.56 (2.36, 5.40)

 < 0.001

1.18 (0.59, 2.37)

0.64

History of myocardial infarction

2.55 (1.28, 5.08)

0.01

1.46 (0.67, 3.17)

0.35

Prior revascularization

3.09 (2.03, 4.71)

 < 0.001

3.02 (1.94, 4.70)

 < 0.001

History of heart failure

3.60 (2.27, 5.70)

 < 0.001

2.70 (1.59, 4.58)

 < 0.001

Medications

 ACEI or ARB

0.90 (0.46, 1.75)

0.75

  

 Antiplatelet

1.60 (0.80, 3.21)

0.19

  

 Beta blocker

0.96 (0.50, 1.87)

0.91

  

 Calcium channel blocker

1.20 (0.61, 2.39)

0.6

  

 Statin

1.85 (0.90, 3.77)

0.09

  

ECG

 No ECG abnormality (reference)

1

-

  

 Major ECG abnormalitya

2.48 (1.50, 4.09)

 < 0.001

1.65 (1.02, 2.66)

0.04

 Minor ECG abnormalitya

0.65 (0.33, 1.28)

0.22

  

CMR

 LV ejection fraction

0.97 (0.96, 0.98)

 < 0.001

0.98 (0.97, 0.99)

0.01

 LV mass index

1.02 (1.02, 1.03)

 < 0.001

1.01 (1.00, 1.02)

0.25

 Myocardial ischemia

3.03 (2.00, 4.57)

 < 0.001

1.81 (1.17, 2.81)

0.01

 Late gadolinium enhancement

3.78 (2.49, 5.72)

 < 0.001

1.55 (0.89, 2.69)

0.12

  1. Abbreviations as in Table 1 to 3
  2. aSee “Methods” section for definitions of major and minor ECG abnormalities