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Table 2 Cox proportional hazard ratios of different risk factors for long-term all-cause mortality

From: Independent and joint effects of high-sensitivity c-reactive protein and hypoalbuminemia on long-term all-cause mortality among coronary artery disease: a prospective and multicenter cohort study

Risk factor

n

Events, n (%)

All-cause mortality HR (95% Cl), P Value

Univariate

Multivariatea

Albumin, g/L

    

Continuous

    

IQR (33.9–39.2)

1449

107 (7.4%)

0.86 (0.83–0.91), < 0.001

0.90 (0.85–0.95), < 0.001

Categories

    

Group 1 (≥ 35)

948

46 (4.9%)

Ref

Ref

Group 2 (< 35)

501

61 (12.2%)

2.49 (1.69–3.66), < 0.001

1.93 (1.20–3.08), 0.006

Tertiles (min–max)

    

T3 (38.1–64.3)

472

15 (3.2%)

Ref

Ref

T2 (34.8–38.1)

488

35 (7.2%)

2.15 (1.17–3.95), 0.014

1.73 (0.86–3.49), 0.12

T1 (18.7—34.8)

474

57 (12.0%)

3.69 (2.08–6.52), < 0.001

2.55 (1.29–5.02), 0.007

P for trend

  

 < 0.001

0.005

hs-CRP, mg/L

    

Continuous

    

IQR (0.96–9.1)

1449

107 (7.4%)

1.01 (1.00–1.01), < 0.001

1.00 (1.00–1.01), 0.18

log10 (hs-CRP)

1449

107 (7.4%)

1.72 (1.31–2.26), < 0.001

1.51 (1.09–2.09), 0.014

Categories

    

Group 1 (≤ 3)

716

29 (4.1%)

Ref

Ref

Group 1 (> 3)

731

78 (10.7%)

2.60 (1.69–3.99), < 0.001

2.49 (1.48–4.17), < 0.001

Tertiles (min–max)

    

T1 (0.18–1.4)

481

23 (4.8%)

Ref

Ref

T2 (1.4–6.0)

481

27 (5.6%)

1.23 (0.71–2.15), 0.46

1.52 (0.81–2.88), 0.20

T3 (6.0–194)

485

57 (11.8%)

2.41 (1.48–3.93), < 0.001

2.10 (1.17–3.78), 0.013

P for trend

  

 < 0.001

0.013

  1. aAdjusted for full multivariate: age > 65, gender, smoking, hypertension, acute myocardial infarction, stroke, diabetes mellitus, percutaneous coronary intervention, ejection fraction reduced heart failure, hyperlipidemia, anemia, angiotensin-converting enzyme inhibitor/angiotensin receptor blockers, β-blockers, statins