Table 1 Participant characteristics at time of atrial fibrillation diagnosis, MarketScan database, 2007–2015
Overall (N = 275,617) | Men (N = 135,850) | Women (N = 139,767) | |
|---|---|---|---|
Age, years | 83.2 (5.4) | 82.5 (5.2) | 83.8 (5.6) |
Prior medical history | |||
Alcohol use | 2520 (0.9) | 1782 (1.3) | 738 (0.5) |
Chronic kidney disease | 68,521 (24.9) | 37,522 (27.6) | 30,999 (22.2) |
Chronic obstructive pulmonary disease | 72,016 (26.1) | 36,890 (27.2) | 35,126 (25.1) |
Coronary artery disease | 128,965 (46.8) | 74,934 (55.2) | 54,031 (38.7) |
Diabetes mellitus | 87,876 (31.9) | 47,727 (35.1) | 40,149 (28.7) |
Dementia | 38,528 (14.0) | 16,728 (12.3) | 21,800 (15.6) |
Depression | 23,461 (8.5) | 8774 (6.5) | 14,687 (10.5) |
Gastrointestinal bleed | 29,117 (10.6) | 14,496 (10.7) | 14,621 (10.5) |
Heart failure | 89,013 (32.2) | 44,330 (32.6) | 44,683 (32.0) |
Hyperlipidemia | 130,423 (47.3) | 67,345 (49.6) | 63,078 (45.1) |
Hypertension | 210,052 (76.2) | 100,749 (74.2) | 109,303 (78.2) |
Intracranial bleed | 5527 (2.0) | 2775 (2.0) | 2752 (2.0) |
Liver disease | 10,918 (4.0) | 5542 (4.1) | 5376 (3.9) |
Myocardial infarction | 30,809 (11.2) | 17,410 (12.8) | 13,399 (9.6) |
Other bleeds | 34,100 (12.4) | 21,094 (15.5) | 13,006 (9.3) |
Peripheral arterial disease | 54,238 (19.7) | 27,967 (20.6) | 26,271 (18.8) |
Stroke | 81,717 (29.7) | 40,556 (29.9) | 41,161 (29.5) |
Medication use | |||
Angiotensin converting enzyme inhibitors | 97,532 (35.4) | 51,987 (38.3) | 45,545 (32.6) |
Angiotensin receptor blockers | 63,464 (23.0) | 27,054 (19.9) | 36,410 (26.1) |
Anti-arrhythmic medication | 31,546 (11.5) | 16,644 (12.3) | 14,902 (10.7) |
Anticoagulant | 111,537 (40.5) | 58,314 (42.9) | 53,223 (38.1) |
Anti-platelet medication | 45,884 (16.7) | 25,382 (18.7) | 20,502 (14.7) |
Beta-blockers | 164,968 (59.9) | 80,043 (59.0) | 84,925 (60.8) |
Calcium channel blockers | 104,583 (40.0) | 45,452 (33.5) | 59,131 (42.3) |
Digoxin | 43,501 (15.8) | 20,388 (15.0) | 23,113 (16.5) |
Diuretics | 94,469 (34.3) | 45,436 (33.5) | 49,033 (35.1) |
Gastrointestinal drugs | 83,380 (30.3) | 38,682 (28.5) | 44,678 (32.0) |
Glucose-lowering medication | 37,508 (13.6) | 21,119 (15.6) | 16,389 (11.7) |
Insulin | 17,370 (6.3) | 9518 (7.0) | 7852 (5.6) |
Lipid lowering medication | 32,841 (11.9) | 18,000 (13.3) | 14,841 (10.6) |
Other diuretics | 31,493 (11.4) | 13,907 (10.2) | 17,586 (12.6) |
Potassium supplements | 61,331 (22.3) | 26,417 (19.5) | 34,914 (25.0) |
Statins | 145,269 (52.7) | 77,585 (57.1) | 67,684 (48.4) |
Sulphonylureas | 28,226 (10.2) | 16,319 (12.0) | 11,907 (8.5) |