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Table 1 Patient demographics and baseline characteristics

From: Pharmacodynamic evaluation and safety assessment of treatment with antibodies to serum amyloid P component in patients with cardiac amyloidosis: an open-label Phase 2 study and an adjunctive immuno-PET imaging study

 

Phase 2 study (Group 1 and 2) (n = 7)

Immuno-PET study (n = 2)

Sex, n (%)

 Male

7 (100)

1 (50)

 Female

0 (0)

1 (50)

Mean (SD) age, years

73.3 (4.07)

77.5 (3.54)

Ethnicity

 Not Hispanic or Latino, n (%)

7 (100)

2 (100)

Race, n (%)

 White

7 (100)

2 (100)

Cardiac amyloidosis type, n (%)

 ATTR-CM

6 (85.7)

2 (100)a

 AL

1 (14.3)

0 (0)

Mean (SD) cumulative miridesap dose, mg

Group 1 (n = 6)

12,519.3 (3245.35)

3394.0 (1406.61)

Group 2 (n = 1)

1291.0

Mean (SD) cumulative dezamizumab dose, mg

Group 1 (n = 6)

5379.5 (1498.67)

330.1 (353.1)

Group 2 (n = 1)

300.0

  1. ATTR-CM transthyretin amyloidosis cardiomyopathy, AL immunoglobulin light chain amyloidosis, PET positron emission tomography, SD standard deviation
  2. aATTR-CM diagnosis not databased