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Table 1 Basic Characteristics of participants born in England and Scotland in UK Biobank

From: Polygenic risk for coronary artery disease in the Scottish and English population

 

England (N = 317,889)

Scotland (N = 31,963)

P-value

Gender***

  

0.0002

F

169,679 (53.4%)

17,411 (54.5%)

 

M

148,210 (46.6%)

14,552 (45.5%)

 

Age (years)

  

0.0519

Mean (SD)

56.7 (± 8.1)

56.6 (± 8.0)

 

BMI***

  

0.0002

Mean (SD)

27.4 (± 4.7)

27.49 (± 4.7)

 

HDL cholesterol (mg/dL)

  

0.1296

Mean (SD)

26.2 (± 6.9)

26.1 (± 6.9)

 

Total cholesterol (mg/dL)*

  

0.0381

Mean (SD)

102.8 (± 20.6)

103.1 (± 20.7)

 

Systolic blood pressure (mmHg)***

  

 < 0.001

Mean (SD)

138.0 (± 18.5)

139.0 (± 18.9)

 

Antihypertensive medication**

  

0.0012

Yes

72,816 (22.9%)

7,577 (23.7%)

 

No

245,073 (77.1%)

24,386 (76.3%)

 

Smoking***

  

 < 0.001

Yes

32,484 (10.2%)

4,078 (12.8%)

 

No

285,405 (89.8%)

27,885 (87.2%)

 

Diabetes***

  

 < 0.001

Yes

24,646 (7.8%)

1,918 (6.0%)

 

No

293,243 (92.3%)

30,045 (94.0%)

 
  1. SD: standard deviation; BMI: body mass index; HDL: high-density lipoprotein
  2. *p < 0.05; **p < 0.01; ***p < 0.001