From: Polygenic risk for coronary artery disease in the Scottish and English population
England (N = 317,889) | Scotland (N = 31,963) | P-value | |
---|---|---|---|
Gender*** | 0.0002 | ||
F | 169,679 (53.4%) | 17,411 (54.5%) | |
M | 148,210 (46.6%) | 14,552 (45.5%) | |
Age (years) | 0.0519 | ||
Mean (SD) | 56.7 (± 8.1) | 56.6 (± 8.0) | |
BMI*** | 0.0002 | ||
Mean (SD) | 27.4 (± 4.7) | 27.49 (± 4.7) | |
HDL cholesterol (mg/dL) | 0.1296 | ||
Mean (SD) | 26.2 (± 6.9) | 26.1 (± 6.9) | |
Total cholesterol (mg/dL)* | 0.0381 | ||
Mean (SD) | 102.8 (± 20.6) | 103.1 (± 20.7) | |
Systolic blood pressure (mmHg)*** | < 0.001 | ||
Mean (SD) | 138.0 (± 18.5) | 139.0 (± 18.9) | |
Antihypertensive medication** | 0.0012 | ||
Yes | 72,816 (22.9%) | 7,577 (23.7%) | |
No | 245,073 (77.1%) | 24,386 (76.3%) | |
Smoking*** | < 0.001 | ||
Yes | 32,484 (10.2%) | 4,078 (12.8%) | |
No | 285,405 (89.8%) | 27,885 (87.2%) | |
Diabetes*** | < 0.001 | ||
Yes | 24,646 (7.8%) | 1,918 (6.0%) | |
No | 293,243 (92.3%) | 30,045 (94.0%) |