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Table 1 Baseline characteristics of patients by PLR tertiles

From: U-shaped relationship between platelet–lymphocyte ratio and postoperative in-hospital mortality in patients with type A acute aortic dissection

Variables

PLR tertiles

P value

T1 (< 112.73)

(n = 90)

T2 (112.73–179)

(n = 90)

T3 (> 179)

(n = 90)

Age (year)

50.93 ± 10.72

49.52 ± 11.65

49.52 ± 11.02

0.618

Sex (male)

69 (76.67%)

57 (63.33%)

63 (70.00%)

0.149

Lymphocyte (109/L)

1.50 (1.20–2.20)

1.20 (1.00–1.40)

0.70 (0.60–1.00)

 < 0.001*

Platelet count (109/L)

127.50 (95–150.75)

174 (147.50–215.25)

181 (148.25–232.75)

 < 0.001*

Hemoglobin (g/L)

121.70 ± 21.11

122.82 ± 19.07

121.01 ± 22.10

0.840

INR

1.11 (1.04–1.24)

1.09 (1.01–1.17)

1.10 (1.04–1.17)

0.501

PT (s)

14.05 (13.22–15.45)

13.80 (12.93–14.70)

14.00 (13.30–14.90)

0.115

APTT (s)

35.60 (31.85–38.98)

33.55 (29.65–37.95)

33.65 (30.70–37.25)

0.389

Smoking

44 (48.89%)

36 (40.00%)

43 (47.78%)

0.427

Alcohol consumption

31 (34.44%)

32 (35.56%)

33 (36.67%)

0.953

Hypertension

65 (72.22%)

60 (66.67%)

62 (68.89%)

0.719

Diabetes mellitus

3 (3.33%)

6 (6.67%)

4 (4.44%)

0.568

Marfan syndrome

3 (3.33%)

10 (11.11%)

4 (4.44%)

0.067

Hemopericardium

9 (10.00%)

6 (6.67%)

10 (11.11%)

0.564

Coronary artery disease

10 (11.11%)

7 (7.78%)

6 (6.67%)

0.539

Cerebrovascular disease

4 (4.44%)

4 (4.44%)

6 (6.67%)

0.740

Chronic renal failure

5 (5.56%)

3 (3.33%)

4 (4.44%)

0.770

Penn class

   

0.479

 Class Aa

55 (61.11%)

48 (53.33%)

48 (53.33%)

 

 Non class Aa

35 (38.89%)

42 (46.67%)

42 (46.67%)

 

CPB time (min)

176 (146–207.25)

174.5 (143.5–202.75)

176 (144.25–197)

0.424

Ventilator use

51 (56.67%)

46 (51.11%)

51 (56.67%)

0.688

Operative time (hour)

11 (9–12)

10 (9–11.75)

10 (8–12)

0.344

Surgery type

   

0.055

 AAR + TAR (TAVR) + FET

42 (46.67%)

49 (54.44%)

42 (46.67%)

 

 Bentall + TAR (TAVR) + FET

27 (30.00%)

16 (17.78%)

15 (16.67%)

 

 David + TAVR + FET

1 (1.11%)

6 (6.67%)

3 (3.33%)

 

 Combine others

20 (22.22%)

19 (21.11%)

30 (33.33%)

 

 Autologous blood transfusion (≥ 500 ml)

20 (22.22%)

31 (34.44%)

32 (35.56%)

0.099

Platelet (therapeutic dose)

   

0.003*

 ≤ 1

44 (48.89%)

53 (58.89%)

66 (73.33%)

 

 > 1

46 (51.11%)

37 (41.11%)

24 (26.67%)

 

Cryoprecipitate (therapeutic dose)

   

0.456

 ≤ 1

53 (58.89%)

58 (64.44%)

61 (67.78%)

 

 > 1

37 (41.11%)

32 (35.56%)

29 (32.22%)

 

RBCs (unit)

   

0.438

 ≤ 10

57 (63.33%)

60 (66.67%)

65 (72.22%)

 

 > 10

33 (36.67%)

30 (33.33%)

25 (27.78%)

 

Plasma (unit)

   

0.099

 ≤ 10

38 (42.22%)

52 (57.78%)

48 (53.33%)

 

 > 10

52 (57.78%)

38 (42.22%)

42 (46.67%)

 

 Postoperative in-hospital mortality

21 (23.33%)

6 (6.67%)

9 (10.00%)

0.002*

  1. Results are expressed as mean ± SD, median (Q1-Q3) or n (%). *, P < 0.05. PLR, platelet-lymphocyte ratio; INR, international normalized ratio; PT, prothrombin time; APTT, activated partial thromboplastin time; CPB, cardiopulmonary bypass; AAR, ascending aorta replacement; TAR, total arch replacement; TAVR, total aortic vascular replacement; FET, frozen elephant trunk; RBCs, red blood cells