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Table 3 Prospective association between baseline SUA and percentage decrease of LDL-C (%)

From: Association between baseline serum uric acid and development of LDL-C level in patients with first acute myocardial infarction

SUA, μmol/L

N

Mean ± SD

Unadjusted model

Adjusted model 1

Adjusted model 2

β(95%CI)

P value

β(95%CI)

P value

β(95%CI)

P value

SUA (per SD)

475

400.96 ± 120.58

4.00 (1.52, 6.48)

0.002

4.37 (1.79, 6.95)

0.001

3.96 (1.44, 6.48)

0.002

Tertiles

 T1 (< 341.7)

158

277.18 ± 49.36

Ref

-

Ref

-

Ref

-

 T2 (≥ 341.7, < 437.0)

158

390.00 ± 26.10

6.07 (0.00, 12.14)

0.051

4.51 (− 1.31, 10.33)

0.130

4.81 (− 0.80, 10.42)

0.094

 T3 (≥ 437.0)

159

534.86 ± 83.86

10.10 (4.03, 16.16)

0.001

8.91 (2.74, 15.07)

0.005

8.57 (2.64, 14.49)

0.005

P for trend

   

0.001

 

0.005

 

0.005

  1. Model 1 was adjusted for sex, BMI, age, hypertension, diabetes, smoke, drink, types of AMI, gout, TG, LDL-C, BUN, CRE, eGFR, AST, ALT, TBIL, statin use, uric acid lowering drugs, diuretics and β receptor blocker; Model 2 was adjusted for sex, BMI, age, hypertension, diabetes, smoke, drink, types of AMI, gout, TG, LDL-C, BUN, CRE, eGFR, AST, ALT, TBIL, statin use, uric acid lowering drugs, diuretics, β receptor blocker, LVEF, culprit vessel and Killip class
  2. SUA, serum uric acid; BMI, body mass index; AMI, acute myocardial infarction; SBP, systolic blood pressure; DBP, diastolic blood pressure; TBil, total bilirubin; DBIL, direct bilirubin; IBIL, indirect bilirubin; ALT, alanine aminotransferase; AST, aspartate aminotransferase; BUN, blood urea nitrogen; CRE, creatinine; eGFR, estimated glomerular filtration rate; TC, total cholesterol; TG, triglyceride; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; LVEF, left ventricular ejection fraction