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Table 4 Hazard ratios for atrial fibrillation recurrence according to candidate biomarkers

From: Total NT-proBNP, a novel biomarker related to recurrent atrial fibrillation

Biomarker

Univariate model

Multivariable model

HR (95%CI)

Pfdr

HR (95%CI)

Pfdr

Total NT-proBNP

1.15 (1.02–1.30)

0.040

1.19 (1.04–1.36)

0.026

NT-proBNP

1.21 (1.09–1.34)

0.002

1.19 (1.06–1.35)

0.016

Ang2

1.15 (1.01–1.30)

0.047

1.07 (0.95–1.20)

0.283

BMP10

1.01 (0.88–1.17)

0.898/

1.09 (0.96–1.25)

0.249

  1. The prediction of AF recurrence was assessed by Cox proportional hazards regression models. Data shown as hazard ratio HR for an increment of 1 SD of baseline biomarker value. The multivariable model was adjusted for sex and > 2 episodes of AF in the six months before inclusion in the GISSI-AF trial. P-value was corrected for multiple testing by means of FDR-correction. HR, hazard ratio; NT-proBNP, N-terminal pro-B type natriuretic peptide; Ang2, angiopoietin 2; BMP10, bone morphogenic protein-10
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BMC Cardiovascular Disorders

ISSN: 1471-2261

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