Fig. 3

Adjusted hazard ratios for MACE associated with increase in coronary artery calcium scores. CACS = coronary arteries calcium score; CHD = coronary heart disease; CI = confidence interval; MACE = major adverse cardiovascular events; MESA = multi-ethnic study of atherosclerosis; PCE = pooled cohort equations; Q = quartiles. MESA 10-year CHD risk score incorporating CACS, presented by quartiles of percent risk. Hazard ratio was adjusted for duration of diabetes, insulin treatment, glycated hemoglobin, presence of retinopathy, nephropathy, neuropathy, creatinine clearance, prior CVA/TIA and medication treatment with aspirin or statin at enrolment. CACS, presented as a continuous variable (Agatston units). Hazard ratio was adjusted for previous variables as well as age, sex, PCE 10-year risk score (%) and MESA (without CACS) 10-year risk score (%)