Skip to main content

Table 4 Hazard ratios (95%CI) for incident ischemic stroke and incident CE per 1 SD change in inflammatory markers in MDC-CV

From: Comparison of risk factors for ischemic stroke and coronary events in a population-based cohort

 

No. of subjects

 

Ischemic stroke

Coronary events

P value for equal associationsd

Events, n

HR (95%CI)

Events, n

HR (95%CI)

Orosomucoid

4742

Model 1

408

1.22 (1.12–1.33)c

537

1.20 (1.11–1.29)c

0.735

Model 2

1.15 (1.05–1.26)b

1.11 (1.02–1.20)a

0.858

Haptoglobin

4364

Model 1

368

1.17 (1.07–1.29)b

487

1.18 (1.09–1.28)c

0.961

Model 2

1.08 (0.97–1.19)

1.07 (0.98–1.17)

0.906

Alpha1-antitrypsin

4715

Model 1

404

1.13 (1.03–1.24)a

529

1.25 (1.16–1.36)c

0.092

Model 2

1.08 (0.98–1.19)

1.21 (1.11–1.31)c

0.093

Ceruloplasmin

4507

Model 1

383

1.09 (0.98–1.21)

502

1.14 (1.05–1.25)b

0.481

Model 2

1.06 (0.95–1.18)

1.10 (1.00–1.21)a

0.567

C3

4790

Model 1

412

1.06 (1.01–1.11)a

540

1.07 (1.03–1.11)b

0.791

Model 2

1.07 (0.97–1.19)

1.09 (0.99–1.19)

0.823

CRP

4634

Model 1

387

1.23 (1.11–1.36)c

507

1.26 (1.16–1.37)c

0.722

Model 2

1.10 (0.99–1.22)

1.12 (1.02–1.23)a

0.758

suPAR

4669

Model 1

392

1.26 (1.16–1.38)c

506

1.23 (1.07–1.33)c

0.599

Model 2

1.16 (1.05–1.29)b

1.13 (1.04–1.24)b

0.693

  1. Model 1: Adjusted for age and sex
  2. Model 2: Adjusted for age, sex, waist circumference, smoking, diabetes, systolic blood pressure, use of anti-hypertensive medication and LDL
  3. ap < 0.05; bp < 0.01; cp < 0.001
  4. dNull hypothesis for the p value is that the variable has the same association with incident ischemic stroke and coronary events